YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: twk-18

General Information:
Name(s) found: twk-18 / CE24811 [WormBase]
Description(s) found:
Found 25 descriptions.
SHOW ALL
  • WBGene00006672 locus:twk-18 TWiK family of potassium channels protein 18 status:Confirmed UniProt:Q18120 protein_id:CCD65384.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 461 amino acids

    Gene Ontology:
    Cellular Component: membrane [ICLink to PubMed article]
    Biological Process: potassium ion transport [IDALink to PubMed article]
    locomotion [IMPLink to PubMed article]
    muscle contraction [IMPLink to PubMed article]
    Molecular Function: outward rectifier potassium channel activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIVAQGVST ILTTFQKTFK GLLPLIILVA YTLLGAWIFW MIEGENEREM LIEQQKERDE  60
   61 LIRRTVYKIN QLQIKRQRRL MTAEEEYNRT AKVLTTFQET LGIVPADMDK DIHWTFLGSI 120
  121 FYCMTVYTTI GYGNIVPGTG WGRFATILYA FIGIPLTVLS LYCLGSLFAK GCKMLWRFFL 180
  181 KSTRVVSKDL SNKISEAADN IEEGTTAITP SAEKTENNDD DLLSFPISGL LLITVIWVIF 240
  241 CAVLFTFLEE WDFGTSLYFT LISFTTIGFG DILPSDYDFM PIVGVLLLIG LSLVSTVMTL 300
  301 IQQQIEALAS GMKDNIDQEY ARALNEARED GEVDEHVDPE EDPENNKKSF DAVISRMNWS 360
  361 KRGLYYLLPD SQKKELAKQS EKKMGRKSIK IQTDNDLLET LIREEILKAE LNNEMHKYTA 420
  421 PRSSHQPKLV YSDVREKEVP IEVVRVEHFN HGNEDYLEHD I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..186] PSI-BLAST 30.69897 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
    2 View Details [187..461] PSI-BLAST 11.221849 Inward rectifier potassium channel Kirbac1.1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • potassium channel activity
    		•  6.4331378592544 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  6.39751759555879 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  6.27599868772094 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  6.14572423982603 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  6.13745115468656 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  5.06264960439093 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.86252983188139 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.77144021609018 bayes_pls_golite062009
  • cation channel activity
    		•  4.45742516382134 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.3961579058414 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  4.13359972196575 bayes_pls_golite062009
  • ion channel activity
    		•  3.86720832958006 bayes_pls_golite062009
  • gated channel activity
    		•  3.81381731911499 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  3.76052840244313 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  3.7587607940377 bayes_pls_golite062009
  • channel activity
    		•  3.7587607940377 bayes_pls_golite062009
  • transporter activity
    		•  2.93091397928047 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.82224868778929 bayes_pls_golite062009
  • G-protein activated inward rectifier potassium channel activity
    		•  2.75125247009886 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.54207434157938 bayes_pls_golite062009
  • ATP-activated inward rectifier potassium channel activity
    		•  2.06424227369337 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  1.70106533585704 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  1.70106533585704 bayes_pls_golite062009
  • binding
    		•  1.53091146101223 bayes_pls_golite062009
  • protein binding
    		•  1.48353517714382 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle