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Protein Overview: map-2

General Information:
Name(s) found: map-2 / CE24146 [WormBase]
Description(s) found:
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  • WBGene00003130 locus:map-2 Methionine aminopeptidase 2 status:Confirmed UniProt:Q9U2V9 protein_id:CAB55167.1 [WormBase]
  • gi|5832829|emb|CAB55167.1| C. elegans protein Y116A8A.9, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17544396|ref|NP_502997.1| Methionine AminoPeptidase family member (map-2) [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE24146 WBGene00003130 locus:map-2 status:Partially_confirmed TR:Q9U2V9 protein_id:CAB55167.1 [wormpep150.fasta]
  • 24146 WBGene00003130 locus:map-2 status:Partially_confirmed TR:Q9U2V9 protein_id:CAB55167.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • insulin-like (49.3 kD) (4R792) [Caenorhabditis elegans]gi|5832829|emb|CAB55167.1| Hypothetical protein Y116A8A.9 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:map-2 status:Partially_confirmed TR:Q9U2V9 protein_id:CAB55167.1 [wormpep115.fasta.reversed]
  • CE24146 status:Partially_confirmed TR:Q9U2V9 protein_id:CAB55167.1 [wormpep80.hongbin]
  • CE24146 WBGene00003130 locus:map-2 status:Confirmed UniProt:Q9U2V9_CAEEL protein_id:CAB55167.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE24146 WBGene00003130 locus:map-2 status:Confirmed UniProt:Q9U2V9_CAEEL protein_id:CAB55167.1| [wormORF-contam.fasta]
  • Hypothetical protein Y116A8A.9 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Methionine AminoPeptidase family member (map-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE24146 WBGene00003130 locus:map-2 status:Confirmed TR:Q9U2V9 protein_id:CAB55167.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE24146 WBGene00003130 locus:map-2 status:Confirmed UniProt:Q9U2V9 protein_id:CAB55167.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE24146 WBGene00003130 locus:map-2 status:Confirmed UniProt:Q9U2V9 protein_id:CAB55167.1 Methionine aminopeptidase 2 [wormpep246-ecoli-contam.fasta]
  • Isoform of H1UBK1, Methionine aminopeptidase 2 OS=Caenorhabditis elegans GN=map-2 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 444 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: gonad development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    proteolysis [IEALink to PubMed article]
    gamete generation [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: methionyl aminopeptidase activity [IEALink to PubMed article]
    metalloexopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPANGKKGK KGGAAKAAAP EEDFDAILAE MQLADAKTAA KEATKKDAKG GKGKANGSAA  60
   61 ATAAPEEAKQ AWQAEIAAMK PIDEQFPDGK FPHGIDESPY YLKGKDGRVA TDRESNEEKK 120
  121 ALDISYEEVW QDYRRSAEAH RQVRKYVKSW IKPGMTMIEI CERLETTSRR LIKEQGLEAG 180
  181 LAFPTGCSLN HCAAHYTPNA GDTTVLQYGD VCKIDYGIHV RGRLIDSAFT VHFDPKFDPL 240
  241 VEAVREATNA GIKESGIDVR LCDVGEIVEE VMTSHEVELD GKSYVVKPIR NLNGHSIAQY 300
  301 RIHAGKTVPI VKGGEQTKME ENEIYAIETF GSTGKGYVHD DMETSHYMKN FELADEKIPL 360
  361 RLQKSKGLLN LIDKNFATLA FCRRWIDRLG ETKYLMALKD LCDKGIVDPY PPLCDVKGCY 420
  421 TAQWEHTILM RPTVKEVVSR GDDY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] PSI-BLAST 63.522879 AMINOPEPTIDASE P FROM E. COLI WITH THE INHIBITOR PRO-LEU
    2 View Details [69..444] PSI-BLAST 92.221849 HUMAN METHIONINE AMINOPEPTIDASE 2 COMPLEXED WITH TNP-470

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  2.60615909541559 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.18503136472662 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.08341148210578 bayes_pls_golite062009
  • transcription activator activity
    		•  1.98504395280033 bayes_pls_golite062009
  • hydrolase activity
    		•  1.43646476372001 bayes_pls_golite062009
  • binding
    		•  1.2577767263541 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.05292713355237 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.89399203910285 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.762255574851485 bayes_pls_golite062009
  • metallopeptidase activity
    		•  0.629480947971878 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.478507702690501 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.42135864069093 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.377243230296854 bayes_pls_golite062009
  • catalytic activity
    		•  0.148551873544128 bayes_pls_golite062009
  • DNA binding
    		•  0.146627179138465 bayes_pls_golite062009
  • protein binding
    		•  0.0709708941336981 bayes_pls_golite062009
  • transferase activity
    		•  0.064832527337659 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  6.94228632297178E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle