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Protein Overview: acs-12

General Information:
Name(s) found: acs-12 / CE18637 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00009106 locus:acs-12 status:Confirmed UniProt:Q9XV68 protein_id:CAB04170.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 550 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: propionate catabolic process, 2-methylcitrate cycle [IEALink to PubMed article]
    teichoic acid biosynthetic process [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    menaquinone biosynthetic process [IEALink to PubMed article]
    siderophore biosynthetic process [IEALink to PubMed article]
    Molecular Function: D-alanine-poly(phosphoribitol) ligase activity [IEALink to PubMed article]
    AMP binding [IEALink to PubMed article]
    acetate-CoA ligase activity [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    propionate-CoA ligase activity [IEALink to PubMed article]
    o-succinylbenzoate-CoA ligase activity [IEALink to PubMed article]
    (2,3-dihydroxybenzoyl)adenylate synthase activity [IEALink to PubMed article]
    ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIIKSKLPNL DIPDKTFHDF LFHEWEKFRE DVALIDNDTF AQFTFQDVMQ KADFIAKSLV  60
   61 YLKVEKSEVV LLVMDWSPAA IYIALGASMA GAAIQVVSPK LQAWEMQFPV KESESRFVFS 120
  121 DPLGLHEIDK LMKTLNREYR IICTGSRDFA NGYPIIEDLA FAAKQNLPLP KIEPDTDIVY 180
  181 LPYSSGIHGK RKGIVTTHKV MVAKTMVMWN TSKHHEFRRG DTTLTMIPLH KQCGLDAILC 240
  241 ALLNGLTVVT EKNFCVHTFM TCIQRYKIRA VHLTPYLMNL MMFEAENHTY NIESLEWVVT 300
  301 GADAVTEELY EEFTEIFPSV KTVTQTYGMT EVGLICRTYN KNYSPSCGQL TANLEMKVLD 360
  361 ILTGKELGPR EKGQICVKGI AAESPYLNNP KATEEHFLDG WRRTGDIGFF DEEGNVHLVD 420
  421 KLKEMIKVFG YQVIPKEIET LLLTHQAVEE AAVVAINNEL SGERPVAFVV LKKGFVATED 480
  481 DLKDYVNKRV IRYKHLVRVN ITQFLPKSAC GTLLRRLLAE AAVMSVASIA EVEKEFVPEL 540
  541 PADMKSILTH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..550] PSI-BLAST 116.0 FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-sulfur bonds
    		•  3.70876535784982 bayes_pls_golite062009
  • acetate-CoA ligase activity
    		•  3.35108612287028 bayes_pls_golite062009
  • acid-thiol ligase activity
    		•  2.89129353633634 bayes_pls_golite062009
  • fatty acid ligase activity
    		•  2.81586165547239 bayes_pls_golite062009
  • long-chain fatty acid-CoA ligase activity
    		•  2.67837372397422 bayes_pls_golite062009
  • CoA-ligase activity
    		•  2.5960476232329 bayes_pls_golite062009
  • catalytic activity
    		•  1.83545185797733 bayes_pls_golite062009
  • ligase activity
    		•  1.03953155205617 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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