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View Structure Prediction Details

Protein: acs-12
Organism: Caenorhabditis elegans
Length: 550 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acs-12.

Description E-value Query
Range
Subject
Range
gi|77996178, gi|... - gi|78044063|ref|YP_360551.1| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...
548.0 [0..4] [527..16]

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Predicted Domain #1
Region A:
Residues: [1-550]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIIKSKLPNL DIPDKTFHDF LFHEWEKFRE DVALIDNDTF AQFTFQDVMQ KADFIAKSLV  60
   61 YLKVEKSEVV LLVMDWSPAA IYIALGASMA GAAIQVVSPK LQAWEMQFPV KESESRFVFS 120
  121 DPLGLHEIDK LMKTLNREYR IICTGSRDFA NGYPIIEDLA FAAKQNLPLP KIEPDTDIVY 180
  181 LPYSSGIHGK RKGIVTTHKV MVAKTMVMWN TSKHHEFRRG DTTLTMIPLH KQCGLDAILC 240
  241 ALLNGLTVVT EKNFCVHTFM TCIQRYKIRA VHLTPYLMNL MMFEAENHTY NIESLEWVVT 300
  301 GADAVTEELY EEFTEIFPSV KTVTQTYGMT EVGLICRTYN KNYSPSCGQL TANLEMKVLD 360
  361 ILTGKELGPR EKGQICVKGI AAESPYLNNP KATEEHFLDG WRRTGDIGFF DEEGNVHLVD 420
  421 KLKEMIKVFG YQVIPKEIET LLLTHQAVEE AAVVAINNEL SGERPVAFVV LKKGFVATED 480
  481 DLKDYVNKRV IRYKHLVRVN ITQFLPKSAC GTLLRRLLAE AAVMSVASIA EVEKEFVPEL 540
  541 PADMKSILTH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 116.0
Match: 1ba3A
Description: FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-sulfur bonds 3.70876535784982 bayes_pls_golite062009
acetate-CoA ligase activity 3.35108612287028 bayes_pls_golite062009
acid-thiol ligase activity 2.89129353633634 bayes_pls_golite062009
fatty acid ligase activity 2.81586165547239 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 2.67837372397422 bayes_pls_golite062009
CoA-ligase activity 2.5960476232329 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
ligase activity 1.03953155205617 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle