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The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action. The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. The biosynthetic process whereby peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione. The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol. The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3. The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action. The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine. The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore. The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid). The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine). The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: siderophore biosynthetic process
Acc: GO:0019290
Aspect: Biological Process
Desc: The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.
Synonyms:
  • GO:0031180
  • siderophore synthesis
  • siderophore anabolism
  • GO:0031178
  • siderochrome biosynthesis
  • siderophore formation
  • siderochrome biosynthetic process
  • siderophore biosynthetic process, peptide formation
  • siderophore biosynthetic process, peptide modification
  • siderophore biosynthesis
Proteins in PDR annotated with:
   This term: 37 [Search]
   Term or descendants: 44 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0019290 - siderophore biosynthetic process (interactive image map)
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