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Protein Overview: aph-2

General Information:
Name(s) found: aph-2 / CE15229 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00000148 locus:aph-2 status:Partially_confirmed UniProt:A5Z2T7 protein_id:CAN99711.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 721 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    protein processing [IEALink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKWLVIVLI IAGIRCDGFS DQVFRTLFIG EGNACYRTFN KTHEFGCQAN RENENGLIVR  60
   61 IDKQEDFKNL DSCWNSFYPK YSGKYWALLP VNLIRRDTIS QLKSSKCLSG IVLYNSGESI 120
  121 HPGDESTAAS HDAECPNAAS DYYLQDKNEE YCERKINSRG AITRDGLMKI DWRIQMVFID 180
  181 NSTDLEIIEK CYSMFNKPKE DGSSGYPYCG MSFRLANMAA GNSEICYRRG KNDAKLFQMN 240
  241 IDSGDAPQLC GAMHSDNIFA FPTPIPTSPT NETIITSKYM MVTARMDSFG MIPEISVGEV 300
  301 SVLTSIISVL AAARSMGTQI EKWQKASNTS NRNVFFAFFN GESLDYIGSG AAAYQMENGK 360
  361 FPQMIRSDRT HIHPIRPNEL DYILEVQQIG VAKGRKYYVH VDGERYQQNK TQTDRVIDRI 420
  421 ERGLRSHAFD LEKPSGSGDR VPPASWHSFA KADAHVQSVL LAPYGKEYEY QRVNSILDKN 480
  481 EWTEDEREKA IQEIEAVSTA ILAAAADYVG VETDEVVAKV DKKLITTIFD CLITSNFWFD 540
  541 CDFMQKLDGG RYHKLFNSYG FNQKSTYISM ESHTAFPTVL HWLTIFALGS DKETLNVKSE 600
  601 KSCSHLGQFQ AMYTYTWQPN PYTGNFSCLK SAIVKKVMVS PAVDSQTPEE EMNTRYSTWM 660
  661 ESVYIIESVN LYLMEDASFE YTMILIAVIS ALLSIFAVGR CSETTFIVDE GEPAAEGGEP 720
  721 L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..195] MSA 1.061969 View MSA. No confident structure predictions are available.
    2 View Details [196..515] PSI-BLAST 34.0 Aminopeptidase
    3 View Details [516..721] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  4.69852272549237 bayes_pls_golite062009
  • hydrolase activity
    		•  4.23257784904124 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.21193944512431 bayes_pls_golite062009
  • metallopeptidase activity
    		•  2.04062448553328 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.5759162922092 bayes_pls_golite062009
  • catalytic activity
    		•  1.3989281287879 bayes_pls_golite062009
  • binding
    		•  0.899461642061592 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  0.891655769761122 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.529831416345723 bayes_pls_golite062009
  • metalloexopeptidase activity
    		•  0.472688733072762 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.385009026435495 bayes_pls_golite062009
  • metallocarboxypeptidase activity
    		•  0.180859448845431 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.140274984043468 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.0966237570696103 bayes_pls_golite062009
  • protein binding
    		•  0.00854198798870509 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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