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Protein Overview: acs-14

General Information:
Name(s) found: acs-14 / CE05585 [WormBase]
Description(s) found:
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  • WBGene00008669 locus:acs-14 status:Confirmed UniProt:Q19339 protein_id:CAA94751.1 [WormBase]
  • pir||T20741 hypothetical protein F11A3.1 - Caenorhabditis elegans [NCBI NR]
  • gi|3875727|emb|CAA94751.1| C. elegans protein F11A3.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17559526|ref|NP_505451.1| hypothetical protein F11A3.1 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE05585 WBGene00008669 4-coumarate-CoA ligase status:Partially_confirmed TR:Q19339 protein_id:CAA94751.1 [wormpep150.fasta]
  • 05585 WBGene00008669 4-coumarate-CoA ligase status:Partially_confirmed TR:Q19339 protein_id:CAA94751.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • ligase family member (60.3 kD) (5J989) [Caenorhabditis elegans]gi|3875727|emb|CAA94751.1| Hypothetical protein F11A3.1 [Caenorhabditis elegans]gi|7498874|pir||T20741 hypothetical protein F11A3.1 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • 4-coumarate-CoA ligase status:Partially_confirmed TR:Q19339 protein_id:CAA94751.1 [wormpep115.fasta.reversed]
  • CE05585 4-coumarate-CoA ligase status:Partially_confirmed TR:Q19339 protein_id:CAA94751.1 [wormpep80.hongbin]
  • CE05585 WBGene00008669 4-coumarate-CoA ligase status:Confirmed UniProt:Q19339_CAEEL protein_id:CAA94751.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE05585 WBGene00008669 4-coumarate-CoA ligase status:Confirmed UniProt:Q19339_CAEEL protein_id:CAA94751.1| [wormORF-contam.fasta]
  • Hypothetical protein F11A3.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • F11A3.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE05585 WBGene00008669 4-coumarate-CoA ligase status:Confirmed TR:Q19339 protein_id:CAA94751.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE05585 WBGene00008669 locus:acs-14 4-coumarate-CoA ligase status:Confirmed UniProt:Q19339 protein_id:CAA94751.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE05585 WBGene00008669 locus:acs-14 4-coumarate-CoA ligase status:Confirmed UniProt:Q19339_CAEEL protein_id:CAA94751.1 [wormbase_c-elegans_197_11-26-2008_reversed.fasta]
  • CE05585 WBGene00008669 locus:acs-14 status:Confirmed UniProt:Q19339 protein_id:CAA94751.1 long-chain-fatty-acid-CoA ligase [wormpep246-ecoli-contam.fasta]
  • Fatty Acid CoA Synthetase family OS=Caenorhabditis elegans GN=acs-14 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 544 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: propionate catabolic process, 2-methylcitrate cycle [IEALink to PubMed article]
    teichoic acid biosynthetic process [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    menaquinone biosynthetic process [IEALink to PubMed article]
    siderophore biosynthetic process [IEALink to PubMed article]
    Molecular Function: D-alanine-poly(phosphoribitol) ligase activity [IEALink to PubMed article]
    AMP binding [IEALink to PubMed article]
    acetate-CoA ligase activity [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    propionate-CoA ligase activity [IEALink to PubMed article]
    o-succinylbenzoate-CoA ligase activity [IEALink to PubMed article]
    (2,3-dihydroxybenzoyl)adenylate synthase activity [IEALink to PubMed article]
    ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHDSTYPPV KISERPYHEM LLDAIDKTIA DGKNKIAFVS GDNPKHFITF EQLRKDAFAV  60
   61 AMYLHSIGFK KDVAAVVLPN VWHYTSFFIG CAINGGAVSG ASALFTDYEL QRQFVDSRAK 120
  121 VVFTYEDFLP KVLLAVKQSP NIQKIIVIPK PVGSSLPAGV VSWNEVVSTP VTALPQVPID 180
  181 VHNDLLVLPY SSGTTGPPKG VMLSHYNFTS MISMYLAIDK SHILDVLDPN WDCYNEKALL 240
  241 FLPFYHVYGF GLLNHCLLKG MTGIVMSHFE PNNFLTAVQN YKVRCLCLVP PIMVFLAKHP 300
  301 ICDKFDLSSV QMIMAGAAPA GKDLIEELKR KYTNLKYIQQ GYGMTECSMA SHLPDLRNDQ 360
  361 PYGSVGKLAS NLVMKIVEPG TDREQPVNQR GEICVRGPTI MLGYLGRPEA TASTVIDGWL 420
  421 HTGDIGYLNE DGNLFIVDRL KELIKVKGLQ VPPAELEDLL LSHPKIRDCA VIGIPDAKAG 480
  481 ELPKAFVVRA DNTLTEQEVK DFVKPKVSPY KQLEGGVEFI EEIPKSAAGK ILRRFLRDRS 540
  541 SAKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..544] PSI-BLAST 109.0 FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-sulfur bonds
    		•  5.10123876514454 bayes_pls_golite062009
  • fatty acid ligase activity
    		•  4.83067429373059 bayes_pls_golite062009
  • long-chain fatty acid-CoA ligase activity
    		•  4.72692389032116 bayes_pls_golite062009
  • acetate-CoA ligase activity
    		•  4.48129067128523 bayes_pls_golite062009
  • acid-thiol ligase activity
    		•  4.28278725989432 bayes_pls_golite062009
  • CoA-ligase activity
    		•  4.12850865352867 bayes_pls_golite062009
  • ligase activity
    		•  2.49556073715112 bayes_pls_golite062009
  • luciferin monooxygenase activity
    		•  2.37933768142137 bayes_pls_golite062009
  • catalytic activity
    		•  1.83545185797733 bayes_pls_golite062009
  • binding
    		•  1.09448261604841 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.843868599988548 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.464663038956639 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.51

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle