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View Structure Prediction Details

Protein: acs-14
Organism: Caenorhabditis elegans
Length: 544 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acs-14.

Description E-value Query
Range
Subject
Range
gi|77996178, gi|... - gi|78044063|ref|YP_360551.1| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...
542.0 [0..2] [543..9]

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Predicted Domain #1
Region A:
Residues: [1-544]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHDSTYPPV KISERPYHEM LLDAIDKTIA DGKNKIAFVS GDNPKHFITF EQLRKDAFAV  60
   61 AMYLHSIGFK KDVAAVVLPN VWHYTSFFIG CAINGGAVSG ASALFTDYEL QRQFVDSRAK 120
  121 VVFTYEDFLP KVLLAVKQSP NIQKIIVIPK PVGSSLPAGV VSWNEVVSTP VTALPQVPID 180
  181 VHNDLLVLPY SSGTTGPPKG VMLSHYNFTS MISMYLAIDK SHILDVLDPN WDCYNEKALL 240
  241 FLPFYHVYGF GLLNHCLLKG MTGIVMSHFE PNNFLTAVQN YKVRCLCLVP PIMVFLAKHP 300
  301 ICDKFDLSSV QMIMAGAAPA GKDLIEELKR KYTNLKYIQQ GYGMTECSMA SHLPDLRNDQ 360
  361 PYGSVGKLAS NLVMKIVEPG TDREQPVNQR GEICVRGPTI MLGYLGRPEA TASTVIDGWL 420
  421 HTGDIGYLNE DGNLFIVDRL KELIKVKGLQ VPPAELEDLL LSHPKIRDCA VIGIPDAKAG 480
  481 ELPKAFVVRA DNTLTEQEVK DFVKPKVSPY KQLEGGVEFI EEIPKSAAGK ILRRFLRDRS 540
  541 SAKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 109.0
Match: 1ba3A
Description: FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-sulfur bonds 5.10123876514454 bayes_pls_golite062009
fatty acid ligase activity 4.83067429373059 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 4.72692389032116 bayes_pls_golite062009
acetate-CoA ligase activity 4.48129067128523 bayes_pls_golite062009
acid-thiol ligase activity 4.28278725989432 bayes_pls_golite062009
CoA-ligase activity 4.12850865352867 bayes_pls_golite062009
ligase activity 2.49556073715112 bayes_pls_golite062009
luciferin monooxygenase activity 2.37933768142137 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
binding 1.09448261604841 bayes_pls_golite062009
transcription regulator activity 0.843868599988548 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.464663038956639 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle