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Protein Overview: unc-97

General Information:
Name(s) found: unc-97 / CE04392 [WormBase]
Description(s) found:
Found 24 descriptions.
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  • WBGene00006826 locus:unc-97 LIM domain-containing protein unc-97 status:Confirmed UniProt:P50464 protein_id:CCD83467.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 348 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    adherens junction [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    integrin complex [IDALink to PubMed article]
    Biological Process: muscle organ development [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    sensory perception of mechanical stimulus [IMPLink to PubMed article]
    cell-cell junction organization [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    protein binding [IEALink to PubMed article][TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSDHNHING DLAHGFENMV CVRCNDGFSM QDQMVNSSGQ VWHSECFVCA QCFEPFPDGI  60
   61 YFEYEGRKYC EHDFHVLFSP CCGKCNEFIV GRVIKAMNAS WHPGCFCCEI CNKQLADVGF 120
  121 LRNAGRALCR ECNEREKAAG HGRYVCHKCH AMIDDGQHIK FRGDSFHPYH FKCKRCNNEL 180
  181 TTASREVNGE LYCLRCHDTM GIPICGACHR PIEERVIAAL GKHWHVEHFV CSVCEKPFLG 240
  241 HRHYERKGLP YCEQHFHKLF GNLCFKCGDP CCGEVFQALQ KTWCVKCFSC SFCDKKLDQK 300
  301 TKFYEFDMKP TCKRCYDRFP TELKKRISES LKDRDVENQR RSMSPGPK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..167] PSI-BLAST 13.69897 Transcription factor IIIA, TFIIIA
    2 View Details [168..348] PSI-BLAST 48.522879 No description for 2i13A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription activator activity
    		•  3.52873291636993 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22082323675675 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.53101891154822 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.22104591928521 bayes_pls_golite062009
  • chromatin binding
    		•  2.18464662431232 bayes_pls_golite062009
  • protein binding
    		•  2.05530362750351 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.64349785387632 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.63161912031789 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.12277938241964 bayes_pls_golite062009
  • signal transducer activity
    		•  1.12277938241964 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.93314267845352 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • tubulin binding
    		•  0.744315484113484 bayes_pls_golite062009
  • microtubule binding
    		•  0.576452165256057 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.53991278722671 bayes_pls_golite062009
  • receptor activity
    		•  0.36635758793995 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.10558148421807 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle