YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: alh-8

General Information:
Name(s) found: alh-8 / CE02183 [WormBase]
Description(s) found:
SHOW ONLY BEST
  • WBGene00000114 locus:alh-8 Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial status:Confirmed UniProt:P52713 protein_id:CAA88946.1 [WormBase]
  • pir||T20828 hypothetical protein F13D12.4 - Caenorhabditis elegans [NCBI NR]
  • gi|71986308|ref|NP_001022078.1| ALdehyde deHydrogenase family member (alh-8) [Caenorhabditis elegans] [NCBI NR]
  • gi|3875820|emb|CAA88946.1| C. elegans protein F13D12.4a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_496505.1| ALDH6A3, ALdehyde deHydrogenase (56.5 kD) (alh-8) [Caenorhabditis elegans] [NCBI NR]
  • gi|1709061|sp|P52713.1|MMSA_CAEEL RecName: Full=Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Short=MMSDH; Short=Malonate-semialdehyde dehydrogenase [acylating]; Flags: Precursor [NCBI NR]
  • Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Caenorhabditis elegans GN=alh-8 PE=3 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE02183 WBGene00000114 locus:alh-8 methylmalonate-semialdehyde dehydrogenase status:Confirmed SW:P52713 protein_id:CAA88946.1 [wormpep150.fasta]
  • 02183 WBGene00000114 locus:alh-8 methylmalonate-semialdehyde dehydrogenase status:Confirmed SW:P52713 protein_id:CAA88946.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • ALDH6A3, ALdehyde deHydrogenase (56.5 kD) (alh-8) [Caenorhabditis elegans]gi|3875820|emb|CAA88946.1| Hypothetical protein F13D12.4a [Caenorhabditis elegans]gi|7499003|pir||T20828 hypothetical protein F13D12.4 - Caenorhabditis elegansgi|1709061|sp|P5271 [nrdb_11152004_Chlamydomonas]
  • locus:alh-8 methylmalonate-semialdehyde dehydrogenase status:Confirmed SW:P52713 protein_id:CAA88946.1 [wormpep115.fasta.reversed]
  • CE02183 methylmalonate-semialdehyde dehydrogenase status:Confirmed SW:P52713 protein_id:CAA88946.1 [wormpep80.hongbin]
  • CE02183 WBGene00000114 locus:alh-8 methylmalonate-semialdehyde dehydrogenase status:Confirmed UniProt:P52713 protein_id:CAA88946.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE02183 WBGene00000114 locus:alh-8 methylmalonate-semialdehyde dehydrogenase status:Confirmed UniProt:P52713 protein_id:CAA88946.1| [wormORF-contam.fasta]
  • Hypothetical protein F13D12.4a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial precursor (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) [nr-271106-contam.fasta]
  • ALdehyde deHydrogenase family member (alh-8) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE02183 WBGene00000114 locus:alh-8 status:Confirmed UniProt:P52713 protein_id:CAA88946.1 Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 523 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [IEALink to PubMed article]
    cytoplasm [IEALink to PubMed article]
    Biological Process: cellular aldehyde metabolic process [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    10-formyltetrahydrofolate catabolic process [IEALink to PubMed article]
    proline biosynthetic process [IEALink to PubMed article]
    valine metabolic process [IEALink to PubMed article]
    betaine biosynthetic process [IEALink to PubMed article]
    one-carbon metabolic process [IEALink to PubMed article]
    Molecular Function: 1-pyrroline-5-carboxylate dehydrogenase activity [IEALink to PubMed article]
    betaine-aldehyde dehydrogenase activity [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article]
    aldehyde dehydrogenase [NAD(P)+] activity [IEALink to PubMed article]
    methylmalonate-semialdehyde dehydrogenase (acylating) activity [IEALink to PubMed article]
    formyltetrahydrofolate dehydrogenase activity [IEALink to PubMed article]
    oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRLARVQP KCQQLAHFST SKSAAAAPTV KLWIDGQAVE SKTTDFVELT NPATNEVIAM  60
   61 VPNATQAEMQ AAVDSAKNAF NTWKNTSPLT RQQCMFKLQA LIKRDMKKLA ESITIEQGKT 120
  121 LPDAEGDVSR GLQVVEHACS VPSLMMGETL PNVSRDMDTH SYRIPLGVTA GICPFNFPAM 180
  181 IPLWMFPVAL ATGNTMVIKP SEQDPGAAQL LVELAKEAGV PDGCVNIIHG QHSAVNFICD 240
  241 NPDIKAISFV GGDAAGKHIY ERGAKNGKRV QSNMGAKNHG VIMADANKEQ TLNQLTAAAF 300
  301 GAAGQRCMAL TTAVLVGEAR AWLPELVEKA KNLKVNAGWK PDTDIGPLIS KQSKARVLRL 360
  361 IESAKKEGAQ VPLDGSNITV PGFENGNFVG PTILAGVKPN MTCYREEIFG PVLVVMEAEN 420
  421 LNEAIEIINN NPYGNGTAIF TSNGATARKF TNEVDVGQIG INVPIPVPLP MFSFTGSRGS 480
  481 FLGDLNFYGK AGIQFYTQWK TVTQYWNESL TELKPQMSFP QLK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..523] PSI-BLAST 144.0 Crystal structure of methylmalonate semialdehyde dehydrogenase from Bacillus subtilis


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle