Protein Overview: ceh-20

General Information:
Name(s) found:	ceh-20 / CE01241 [WormBase]
Description(s) found: Found 21 descriptions. SHOW ALL	WBGene00000443 locus:ceh-20 Homeobox protein ceh-20 status:Confirmed UniProt:P41779 protein_id:CCD63401.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	338 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA ][IEA]
Biological Process:	negative regulation of vulval development [IMP ] locomotory behavior [IMP ] determination of adult lifespan [IMP] positive regulation of growth rate [IMP] embryonic development ending in birth or egg hatching [IMP] post-embryonic body morphogenesis [IMP] mesoderm development [IMP] anterior/posterior pattern formation [TAS] regulation of transcription, DNA-dependent [IEA] oviposition [IMP] cell migration [IMP] positive regulation of multicellular organism growth [IMP]
Molecular Function:	DNA binding [TAS] transcription factor activity [IEA] protein binding [IDA] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGTHPANLS ELLDAVLKIN EQTLDDNDSA KKQELQCHPM RQALFDVLCE TKEKTVLTVR  60
   61 NQVDETPEDP QLMRLDNMLV AEGVAGPDKG GSLGSDASGG DQADYRQKLH QIRVLYNEEL 120
  121 RKYEEACNEF TQHVRSLLKD QSQVRPIAHK EIERMVYIIQ RKFNGIQVQL KQSTCEAVMI 180
  181 LRSRFLDARR KRRNFSKQAT EVLNEYFYGH LSNPYPSEEA KEDLARQCNI TVSQVSNWFG 240
  241 NKRIRYKKNM AKAQEEASMY AAKKNAHVTL GGMAGNPYGM LPGAAAAAGL LNPYNPMNIP 300
  301 GQDTLHMGMP PFDLSVYNPQ LMAAAQYQQQ MDNADKNS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..179]	PSI-BLAST	11.39794	Pax-6
2	View Details	[180..338]	PSI-BLAST	19.522879	pbx1

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
transcription regulator activity	3.19298379377617	bayes_pls_golite062009
DNA binding	2.87605703911271	bayes_pls_golite062009
binding	2.82931587763241	bayes_pls_golite062009
nucleic acid binding	2.64432967912966	bayes_pls_golite062009
transcription factor activity	2.42668242022822	bayes_pls_golite062009
sequence-specific DNA binding	2.01558895662904	bayes_pls_golite062009
transcription repressor activity	1.96316398225504	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.77114246571754	bayes_pls_golite062009
transcription activator activity	1.38536646126001	bayes_pls_golite062009
transcription factor binding	1.1887755957055	bayes_pls_golite062009
protein binding	0.730593483550931	bayes_pls_golite062009
chromatin binding	0.680605031532259	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.57338514991304	bayes_pls_golite062009
transcription corepressor activity	0.233718578386381	bayes_pls_golite062009

2

Term	Confidence	Notes
transcription regulator activity	3.19298379377617	bayes_pls_golite062009
DNA binding	2.87605703911271	bayes_pls_golite062009
binding	2.82931587763241	bayes_pls_golite062009
nucleic acid binding	2.64432967912966	bayes_pls_golite062009
transcription factor activity	2.42668242022822	bayes_pls_golite062009
sequence-specific DNA binding	2.01558895662904	bayes_pls_golite062009
transcription repressor activity	1.96316398225504	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.77114246571754	bayes_pls_golite062009
transcription activator activity	1.38536646126001	bayes_pls_golite062009
transcription factor binding	1.1887755957055	bayes_pls_golite062009
protein binding	0.730593483550931	bayes_pls_golite062009
chromatin binding	0.680605031532259	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.57338514991304	bayes_pls_golite062009
transcription corepressor activity	0.233718578386381	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.91

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle