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Protein Overview: apc-11

General Information:
Name(s) found: apc-11 / CE00978 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00000145 locus:apc-11 status:Confirmed UniProt:Q20052 protein_id:CAA86328.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 135 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article]
    Biological Process: embryonic development [IMPLink to PubMed article]
    cyclin catabolic process [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    meiotic chromosome segregation [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    meiosis [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQQIQMDEQ ENDESQGNDD QQNMSMSSSE LHTMQDDHPG ILLKTNTRMS ITVKKLHVCG  60
   61 EWKWLQGGED TCGICRMEFE SACNMCKFPG DDCPLVLGIC RHAFHRHCID KWIAAPTNQP 120
  121 RAQCPLCRQD WTIVE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] PSI-BLAST 14.522879 Crystal Structure of The Cand1-Cul1-Roc1 Complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  10.2497392096259 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  10.0460587929138 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  8.99384576623969 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  7.6988425139962 bayes_pls_golite062009
  • ligase activity
    		•  3.92677358871643 bayes_pls_golite062009
  • binding
    		•  2.58862749918018 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  2.41658628840288 bayes_pls_golite062009
  • protein binding
    		•  1.49775478023418 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  1.2126425713931 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  1.03469202541773 bayes_pls_golite062009
  • transcription factor binding
    		•  0.90065892745057 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.779340816536763 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.708499177773075 bayes_pls_golite062009
  • hydrolase activity
    		•  0.52386813728704 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.50197530717959 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.393708074680332 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.392372133643049 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  0.265769062717221 bayes_pls_golite062009
  • DNA binding
    		•  0.227671243150662 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
  • enzyme binding
    		•  0.104373352314595 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle