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Protein Overview: acs-7

General Information:
Name(s) found: acs-7 / CE00869 [WormBase]
Description(s) found:
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  • WBGene00007228 locus:acs-7 status:Confirmed UniProt:Q17577 protein_id:CAA84640.1 [WormBase]
  • pir||T18841 hypothetical protein C01G6.7 - Caenorhabditis elegans [NCBI NR]
  • gi|3873862|emb|CAA84640.1| C. elegans protein C01G6.7, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17531443|ref|NP_495979.1| hypothetical protein C01G6.7 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE00869 WBGene00007228 4-coumarate-coA ligase status:Partially_confirmed TR:Q17577 protein_id:CAA84640.1 [wormpep150.fasta]
  • 00869 WBGene00007228 4-coumarate-coA ligase status:Partially_confirmed TR:Q17577 protein_id:CAA84640.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • ligase (60.6 kD) (2J583) [Caenorhabditis elegans]gi|3873862|emb|CAA84640.1| Hypothetical protein C01G6.7 [Caenorhabditis elegans]gi|7495145|pir||T18841 hypothetical protein C01G6.7 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • 4-coumarate-coA ligase status:Partially_confirmed TR:Q17577 protein_id:CAA84640.1 [wormpep115.fasta.reversed]
  • CE00869 4-coumarate-coA ligase status:Partially_confirmed TR:Q17577 protein_id:CAA84640.1 [wormpep80.hongbin]
  • CE00869 WBGene00007228 4-coumarate-coA ligase status:Partially_confirmed UniProt:Q17577_CAEEL protein_id:CAA84640.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE00869 WBGene00007228 4-coumarate-coA ligase status:Partially_confirmed UniProt:Q17577_CAEEL protein_id:CAA84640.1| [wormORF-contam.fasta]
  • C01G6.7 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C01G6.7 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE00869 WBGene00007228 locus:acs-7 4-coumarate-coA ligase status:Partially_confirmed UniProt:Q17577 protein_id:CAA84640.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE00869 WBGene00007228 locus:acs-7 4-coumarate-coA ligase status:Partially_confirmed UniProt:Q17577_CAEEL protein_id:CAA84640.1 [wormbase_c-elegans_197_11-26-2008_reversed.fasta]
  • CE00869 WBGene00007228 locus:acs-7 4-coumarate-coA ligase status:Confirmed UniProt:Q17577 protein_id:CAA84640.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE00869 WBGene00007228 locus:acs-7 status:Confirmed UniProt:Q17577 protein_id:CAA84640.1 long-chain-fatty-acid-CoA ligase [wormpep246-ecoli-contam.fasta]
  • Fatty Acid CoA Synthetase family OS=Caenorhabditis elegans GN=acs-7 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 540 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: propionate catabolic process, 2-methylcitrate cycle [IEALink to PubMed article]
    teichoic acid biosynthetic process [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    menaquinone biosynthetic process [IEALink to PubMed article]
    siderophore biosynthetic process [IEALink to PubMed article]
    Molecular Function: D-alanine-poly(phosphoribitol) ligase activity [IEALink to PubMed article]
    AMP binding [IEALink to PubMed article]
    acetate-CoA ligase activity [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    propionate-CoA ligase activity [IEALink to PubMed article]
    o-succinylbenzoate-CoA ligase activity [IEALink to PubMed article]
    (2,3-dihydroxybenzoyl)adenylate synthase activity [IEALink to PubMed article]
    ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFHGEQLEN HDKPVHEVLL ERFKVHQEKD PDNVAFVTAE NEDDSLGFQQ LGKKVLQISE  60
   61 WFVENGYKKG DVFLLASYNN WRCFAAALGA WRAGLIVSAA ASQFTSFEMN YQIEDSQSQV 120
  121 ILVDKHTLPV VQEACKNLKF VKQIISISAN PPSPVIKFDV LTSRLVRNLK MPLIDPKNDI 180
  181 VFLPYSSGTT GKPKGVMISH LNFSMMLESS LRFFDANAKA IGLPPDFVLP YDLHFLPMYH 240
  241 AMGMFRTLLT SYRGTTQIMF TKFDMELMLK NIEKYSIMVL SLVPAIAVRM LNSPLLQKYD 300
  301 VSSLVSVTVG SAPFPESASK KLKQLLPNVN IVQGYGMTEL TFATHLQSPG SPDGSVGRLV 360
  361 PGTSMKVKKE DGTLCGPHEI GELWIKGPQM MKGYWKKEQQ TNELLDEHGF MRTGDIVYFD 420
  421 KNGETFICDR IKELIKVNAK QVAPAELESV ILEHDDVADV CVFGVDDASS GERPVACVVS 480
  481 KRGRDMETSK AIMKHINQKL ARYKHIKEIE FVSEIMRTGT GKLLRRAMKK AFLDAKKAKL 540
  541

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..540] PSI-BLAST 112.0 FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-sulfur bonds
    		•  5.10123876514454 bayes_pls_golite062009
  • fatty acid ligase activity
    		•  4.83067429373059 bayes_pls_golite062009
  • long-chain fatty acid-CoA ligase activity
    		•  4.72692389032116 bayes_pls_golite062009
  • acetate-CoA ligase activity
    		•  4.48129067128523 bayes_pls_golite062009
  • acid-thiol ligase activity
    		•  4.28278725989432 bayes_pls_golite062009
  • CoA-ligase activity
    		•  4.12850865352867 bayes_pls_golite062009
  • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
    		•  2.74744781333102 bayes_pls_golite062009
  • Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity
    		•  2.74744781333102 bayes_pls_golite062009
  • luciferin monooxygenase activity
    		•  2.67396462766343 bayes_pls_golite062009
  • ligase activity
    		•  2.49556073715112 bayes_pls_golite062009
  • catalytic activity
    		•  1.83545185797733 bayes_pls_golite062009
  • binding
    		•  0.903437109563498 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.464663038956639 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.245590924269919 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle