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View Structure Prediction Details

Protein: acs-7
Organism: Caenorhabditis elegans
Length: 540 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acs-7.

Description E-value Query
Range
Subject
Range
gi|77996178, gi|... - gi|78044063|ref|YP_360551.1| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...
533.0 [0..4] [537..14]

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Predicted Domain #1
Region A:
Residues: [1-540]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFHGEQLEN HDKPVHEVLL ERFKVHQEKD PDNVAFVTAE NEDDSLGFQQ LGKKVLQISE  60
   61 WFVENGYKKG DVFLLASYNN WRCFAAALGA WRAGLIVSAA ASQFTSFEMN YQIEDSQSQV 120
  121 ILVDKHTLPV VQEACKNLKF VKQIISISAN PPSPVIKFDV LTSRLVRNLK MPLIDPKNDI 180
  181 VFLPYSSGTT GKPKGVMISH LNFSMMLESS LRFFDANAKA IGLPPDFVLP YDLHFLPMYH 240
  241 AMGMFRTLLT SYRGTTQIMF TKFDMELMLK NIEKYSIMVL SLVPAIAVRM LNSPLLQKYD 300
  301 VSSLVSVTVG SAPFPESASK KLKQLLPNVN IVQGYGMTEL TFATHLQSPG SPDGSVGRLV 360
  361 PGTSMKVKKE DGTLCGPHEI GELWIKGPQM MKGYWKKEQQ TNELLDEHGF MRTGDIVYFD 420
  421 KNGETFICDR IKELIKVNAK QVAPAELESV ILEHDDVADV CVFGVDDASS GERPVACVVS 480
  481 KRGRDMETSK AIMKHINQKL ARYKHIKEIE FVSEIMRTGT GKLLRRAMKK AFLDAKKAKL 540
  541 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 112.0
Match: 1ba3A
Description: FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-sulfur bonds 5.10123876514454 bayes_pls_golite062009
fatty acid ligase activity 4.83067429373059 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 4.72692389032116 bayes_pls_golite062009
acetate-CoA ligase activity 4.48129067128523 bayes_pls_golite062009
acid-thiol ligase activity 4.28278725989432 bayes_pls_golite062009
CoA-ligase activity 4.12850865352867 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) 2.74744781333102 bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity 2.74744781333102 bayes_pls_golite062009
luciferin monooxygenase activity 2.67396462766343 bayes_pls_golite062009
ligase activity 2.49556073715112 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
binding 0.903437109563498 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.464663038956639 bayes_pls_golite062009
transcription regulator activity 0.245590924269919 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle