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Protein Overview: SPBC1105.07c

General Information:
Name(s) found: SPBC1105.07c [Sanger Pombe]
Description(s) found:
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  • pir||T39284 hypothetical protein SPBC1105.07c - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74626367|sp|Q9Y820.1|YON7_SCHPO RecName: Full=PCI domain-containing protein C1105.07c [NCBI NR]
  • gi|5531469|emb|CAB50970.1| nuclear pore associated protein Thp1-Sac3 complex subunit (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113255|ref|NP_596463.1| nuclear pore associated protein Thp1-Sac3 complex subunit (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • nuclear pore associated protein Thp1-Sac3 complex subunit [Sanger Pombe]
  • PCI domain-containing protein C1105.07c OS=Schizosaccharomyces pombe GN=SPBC1105.07c PE=2 SV=1 [Swiss-Prot]
  • CONSERVED PROTEIN; PUTATIVE PINT DOMAIN: Q9Y820; [pompepVF.fasta]
  • CONSERVED HYPOTHETICAL PROTEIN; PUTATIVE PINT DOMAIN: Q9Y820; [pompepV13]
  • Hypothetical protein [pompep4896]
  • |||conserved eukaryotic protein [pompepnew.fasta]
  • SPBC1105.07c protein [4896.FASTAC]
  • |||THO complex (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • hypothetical protein [Schizosaccharomyces pombe]gi|5531469|emb|CAB50970.1| SPBC1105.07c [Schizosaccharomyces pombe]gi|7491315|pir||T39284 hypothetical protein SPBC1105.07c - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||THO complex |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (Q9Y820) Hypothetical protein [pompep4896_normal_reversed]
  • |||nuclear pore associated protein Thp1-Sac3 complex subunit |Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC1105.07c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC1105.07c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • PCI domain-containing protein C1105.07c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC1105.07c PE=4 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 442 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    nucleus [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    transcription export complex [ISS]
    nuclear pore [ISSLink to PubMed article]
    Biological Process: RNA elongation from RNA polymerase II promoter [ISSLink to PubMed article]
    Molecular Function: RNA binding [ISS]
    double-stranded DNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNDFLQTL SNAVGEKNSN TLEKCIILDP SEPSFQQLSK TLFLDRKGKN KLNGTIQKEF  60
   61 GRIRGWKELV TTYFEYVENA ASSPDQRKWE LLQNLYSNLT TCFSHIDGAW LCTIVKRVSK 120
  121 LYVKLSLQLD TSTPTLEDSF DGNGFIQRKY VSDASRNVLR TFNSILSDRQ QNINPSKKDA 180
  181 IFCIANLLCL LYFRLKQIRL CQTIQANVIS SGADISRATM AELVTFRYYL GRCHLYQRKI 240
  241 HQAKDHLLFS FLQCPDECYH QKRLSLIYLT TCLLILGKSP TKGLLEKYKL TAAFEPLIKA 300
  301 LKSGDIKSFR LSLEDNSRRK WFIKRGIYLT LLDRCEIILW RNLFRKVFLF TFEQSQKTPH 360
  361 VSGSYLLTAA RLSTNDNSYD MDDVECICVS LIDQGYIKGY IIHASSTLVL KKDPSFGFSV 420
  421 IESLMPIARN DHAEKEFFHA NA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..172] MSA 1.157969 View MSA. No confident structure predictions are available.
    2 View Details [173..316] MSA 1.168979 View MSA. No confident structure predictions are available.
    3 View Details [317..442] FFAS03 1.78 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  5.23858959608048 bayes_pls_golite062009
  • DNA binding
    		•  4.54024488199476 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.30331577005505 bayes_pls_golite062009
  • binding
    		•  3.89976494610525 bayes_pls_golite062009
  • transcription factor activity
    		•  3.82269332595313 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.41045867230388 bayes_pls_golite062009
  • transcription activator activity
    		•  2.13702350917359 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.12567455635303 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.9708626903609 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.28654223481433 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  1.19572229887868 bayes_pls_golite062009
  • RNA binding
    		•  0.999156053511857 bayes_pls_golite062009
  • transcription factor binding
    		•  0.752335897765285 bayes_pls_golite062009
  • protein binding
    		•  0.749376520208656 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.490809930581315 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.300710367763552 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.171423850692861 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle