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Protein Overview: vas1

General Information:
Name(s) found: vas1 / SPAC4A8.08c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • mitochondrial valine-tRNA ligase Vas1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 950 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: valyl-tRNA aminoacylation [ISSLink to PubMed article]
    mitochondrial translation [RCALink to PubMed article]
    Molecular Function: valine-tRNA ligase activity [ISSLink to PubMed article]
    ATP binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFHFQRSFSS RKAHGLLSFK NRNYIHIEAP FDIAAIQDGW NIIRKHIHYP KPKSIEAPMF  60
   61 PILLPPPNIT GKLHIGHALT ITIQDALARF YAMHGYKVSF RPGTDHAGIA TQSVVEKYLQ 120
  121 KKGVYRNQLS KDELLSSIHS WQVKYQKSII NQLKSFEAIF DWDNIFYTMD QNRSEAVNEA 180
  181 FISLFNAGLI YRANRFVNWC PKLESAVSDI EVESQQINKP VTKYVDNTPV EFGWLYEISY 240
  241 QLEGSDNEQL NVSTTRPETI FGDRAIAVSP HDERYKKYVG RFVKHPLIDD LLIPVICDNA 300
  301 VDRHFGTGVL KITPMHSIVD YEIAKRHNID CVSIMDKSGN LINCSKEVNG MNRLKARSKI 360
  361 VRLLQQRNRL VEQVPHSLIL SVCSRTGDVI EPVMVPQWYL SVDSLKKEVL KSSNKLKLVP 420
  421 SLARKEWDSW FKKMGDWCIS RQIWWGHQIP VWKILEEDKW IAAPNYEKAL QLSVGKSVSQ 480
  481 DSDVLDTWFS SALLPLSAFG WPKSKDIQPL PFIESGQDIL FFWIARMALL CKYFSNELPF 540
  541 KEIILHPLVR DSEGRKMSKS LGNVIDPMDI INGVTLENMK KALLEGNLPI SEVHKSSKQM 600
  601 EKAFPNGIPA QGIDIFRYGL FLCLHHEQRI LLDMNSFSDA HRFVSKLWNL ARYFNQYKDK 660
  661 ENPLKLTDSQ RQRISLLKMA TYSKLHHAVE GVKESFEQRK FFNAADIMKN FLLNDLSSVY 720
  721 VELTRFDVKD SKSSAYEVYR VFSDILHIFL KLIHPIVPCI SGVMLHSKII PERKNSEFLS 780
  781 FPTSQQECLL VHDNQAEVVV QNAYDVLIQL RKLESPLNKS PSREHTVYIS TSLEPLKYFY 840
  841 DAIEQSTNLK LKSISQEDTI DLMRNQTFIL SRISSDTILL VPKKLYPSKR KKLRKNLDDL 900
  901 QKKLDKIQHT TSSSGYEKAP SYIKLKNCEL QKDILVKIQD IKQALLNTEI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..950] PSI-BLAST 1000.0 Valyl-tRNA synthetase (ValRS) C-terminal domain; Valyl-tRNA synthetase (ValRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • valine-tRNA ligase activity
    		•  7.13767629265822 bayes_pls_golite062009
  • leucine-tRNA ligase activity
    		•  7.03538514482698 bayes_pls_golite062009
  • isoleucine-tRNA ligase activity
    		•  6.38633897147986 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.56893064485672 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.50161401062914 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • binding
    		•  0.485102284225571 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.449504767632354 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.2293846471193 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.126511747475258 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009
  • mRNA binding
    		•  2.82524485163416E-5 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle