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Protein Overview: SPCC1919.03c

General Information:
Name(s) found: SPCC1919.03c [Sanger Pombe]
Description(s) found:
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  • pir||T41228 5'-amp-activated protein kinase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74583069|sp|P78789.2|YC63_SCHPO RecName: Full=Uncharacterized protein C1919.03c [NCBI NR]
  • gi|4107306|emb|CAA22634.1| AMP-activated protein kinase beta subunit (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19075985|ref|NP_588485.1| AMP-activated protein kinase beta subunit (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • AMP-activated protein kinase beta subunit [Sanger Pombe]
  • Uncharacterized protein C1919.03c OS=Schizosaccharomyces pombe GN=SPCC1919.03c PE=1 SV=2 [Swiss-Prot]
  • PUTATIVE 5'-AMP-ACTIVATED PROTEIN KINASE; POSSIBLE REGULATION OF FATTY ACID SYNTHESIS BY THE PHOSPHORYLATION OF ACETYL-COA CARBOXYLASE; POSSIBLY REGULATES CARBOHYDRATE METABOLISM; SIMILAR TO S. CEREVISIAE SIP2; SUBCELLULAR LOCALIZATION OF GFP FUSION- [pompepVF.fasta]
  • PUTATIVE 5'-AMP-ACTIVATED PROTEIN KINASE; PUTATIVE REGULATION OF FATTY ACID SYNTHESIS BY THE PHOSPHORYLATION OF ACETYL-COA CARBOXYLASE; POSSIBLY ALSO REGULATES CARBOHYDRATE METABOLISM BY SIMILARITY TO S. CEREVISIAE SIP2- A PROTEIN THAT INTERACTS WITH S [pompepV13]
  • Putative 5'-AMP-activated protein kinase C1919.03C [pompep4896]
  • |||putative 5'-amp-activated protein kinase beta subunit [pompepnew.fasta]
  • SPCC1919.03c protein [4896.FASTAC]
  • |||5'-amp-activated protein kinase beta subunit (predicted)|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • 5'-amp-activated protein kinase [Schizosaccharomyces pombe]gi|4107306|emb|CAA22634.1| SPCC1919.03c [Schizosaccharomyces pombe]gi|7489993|pir||T41228 5'-amp-activated protein kinase - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||5'-amp-activated protein kinase beta subunit |Schizosaccharomyces pombe|chr 3|||Manual [pompep2242005.fasta]
  • (P78789) Putative 5'-AMP-activated protein kinase C1919.03C [pompep4896_normal_reversed]
  • |||AMP-activated protein kinase beta subunit |Schizosaccharomyces pombe|chr 3|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPCC1919.03c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPCC1919.03c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |amk2||AMP-activated protein kinase beta subunit Amk2|Schizosaccharomyces pombe|chr 3|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Uncharacterized protein C1919.03c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC1919.03c PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 298 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISSLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    plasma membrane [ISSLink to PubMed article]
    AMP-activated protein kinase complex [ISSLink to PubMed article]
    Biological Process: signal transduction [ISSLink to PubMed article]
    regulation of catalytic activity [ICLink to PubMed article]
    protein amino acid phosphorylation [ICLink to PubMed article]
    cellular response to glucose starvation [ISSLink to PubMed article]
    regulation of phosphorylation [ICLink to PubMed article]
    Molecular Function: protein kinase regulator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNVQSQEGE TRAHAVPSQD ATTTPDNANN VPKEPRAQSM ISIAADDLNQ EGEMSDDNQQ  60
   61 EGGNNRTSQN GTSGSSGHTK RRSQTSGKKT HQPYSGPCVP TIIRWRGGGE VVYVTGSFSR 120
  121 WKKKIQLLKS EDYTVLLQLR PGTQRFKFLV DGIWCCSSDF PTATDAEGNL YNYLEVEANE 180
  181 KLGASIDERL SQVHTDLPME EKSESEQYST EIPAFLTSNT LQELKLPKPP SLPPHLEKCI 240
  241 LNSNTAYKED QSVLPNPNHV LLNHLAAANT QLGVLALSAT TRYHRKYVTT AMFKNFDV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..93] deduced N/A No confident structure predictions are available.
    2 View Details [94..298] PSI-BLAST 55.69897 No description for 2qlvB was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • AMP-activated protein kinase activity
    		•  4.78975226545815 bayes_pls_golite062009
  • binding
    		•  2.65544526722793 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.66390525860632 bayes_pls_golite062009
  • kinase activity
    		•  1.64560031716993 bayes_pls_golite062009
  • cation channel activity
    		•  1.61654093209843 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  1.56948414427108 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  1.56948414427108 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.53194692728729 bayes_pls_golite062009
  • protein binding
    		•  1.50286160643298 bayes_pls_golite062009
  • gated channel activity
    		•  1.48812502999143 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.46948685366075 bayes_pls_golite062009
  • protein kinase activity
    		•  1.44964326848891 bayes_pls_golite062009
  • transferase activity
    		•  1.26709925711174 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.12993648323166 bayes_pls_golite062009
  • signal transducer activity
    		•  1.12993648323166 bayes_pls_golite062009
  • ion channel activity
    		•  1.10689326077049 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.726369450752205 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  0.252254893587557 bayes_pls_golite062009
  • potassium channel activity
    		•  0.0778382534131277 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.0457994134318782 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle