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Protein Overview: SPCC645.13

General Information:
Name(s) found: SPCC645.13 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
SHOW ALL
  • transcription elongation regulator [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 721 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: negative regulation of RNA elongation from RNA polymerase II promoter [ISSLink to PubMed article]
    Molecular Function: transcription elongation regulator activity [ISSLink to PubMed article]
    zinc ion binding [IEA]
    small conjugating protein ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRKSTRRTA KASEKPPETV VRCVCKSQED IGDTWVQCDG CDCWQHASCV GLADKDIPES  60
   61 YYCEVCHSRS DVSSQVQNSP NKDEEHQTAD LLASNEGNEK NNEENNVVSS DSKEAITKES 120
  121 GAELESSEPA STNSNVGMTT RSGRQSPRTP IGSTTPKSSH SPPSTRKRRG SVGTTATHTK 180
  181 RSKNAPKTSP KDASNETADQ EKELSLHTSI DEIQNPVRKS VAKAWVSVFE KIIEKAKLEG 240
  241 VQGLEDLNST SLALQLEHIM FMVLSYTTDH SLTPNNKYRE KFRALRFNLV DDKNPAFRAR 300
  301 VLKNEISFND LVNLSSEEMA NPDLKNLAEE IRQQSTENTV IKQHLIAPRD RLLDEDKLTQ 360
  361 QDELGIAEND DAMFPKPPGE LVAPISIAEE EPTIDSKSPT LPEHNPLSED DTSNGDKAAK 420
  421 RKGSFNDTKP IVNVPSIVEI DDPTILDIVE EEPLARNDSF SSPYSPAEDM AEESEFFGMK 480
  481 EKIWTGKVKM ATVSEFHANA LNLFGDVSAS HLFEILSATA LIEGRISVSS VLQYFHALRK 540
  541 TPSKEIIAVL FVPTEQNSQG FDILYDYFVK RNRYGVLHSK SNSVKDAYII PMPSGNSVPE 600
  601 LLDLLPKVDL PKDRNFQYFM GLFVLNKSSS RHESVERATP ITTSTNGIPS TYQSASGTPT 660
  661 NPVHSYPSLE SIINALTPSD MLLIKDVVEN NPQIRANPSL AINPQFMQNA ISAAQKKASK 720
  721 Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..81] PSI-BLAST 12.69897 No description for 2f6jA was found.
    2 View Details [82..178] deduced N/A No confident structure predictions are available.
    3 View Details [179..360] PSI-BLAST 11.154902 No description for 2dmeA was found.
    4 View Details [361..447] deduced N/A No confident structure predictions are available.
    5 View Details [448..645] FFAS03 1.42 Crystal structure of the SPOC domain of the human transcriptional corepressor, SHARP.
    6 View Details [646..721] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • DNA binding
    		•  3.54473441396096 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.48558304847931 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.99210735079034 bayes_pls_golite062009
  • binding
    		•  2.41724497205118 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.05998863112202 bayes_pls_golite062009
  • promoter binding
    		•  1.83726450182234 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.4747942371973 bayes_pls_golite062009
  • transcription activator activity
    		•  1.38544336130022 bayes_pls_golite062009
  • transcription factor activity
    		•  1.36469181687855 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.10125855381509 bayes_pls_golite062009
  • protein binding
    		•  1.08484616730639 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.761344747515317 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.72942170277234 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.486136971288514 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.468110073157235 bayes_pls_golite062009
  • helicase activity
    		•  0.409609667937952 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.364602306790165 bayes_pls_golite062009
  • telomeric DNA binding
    		•  0.323407552453846 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.311579649994958 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.311579649994958 bayes_pls_golite062009
  • catalytic activity
    		•  0.284946544609129 bayes_pls_golite062009
  • transcription factor binding
    		•  0.147270026435341 bayes_pls_golite062009
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle