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Protein Overview: sfp1

General Information:
Name(s) found: sfp1 / SPAC16.05c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • transcription factor Sfp1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 442 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [ISSLink to PubMed article]
    cellular response to stress [ISSLink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [RCALink to PubMed article]
    Molecular Function: transcription factor activity [ISSLink to PubMed article]
    zinc ion binding [IEA]
    specific RNA polymerase II transcription factor activity [RCALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSLALPINK PSHHNVNYNG NSFNSIHATS FGMSPQSWGN SFSGQAWLRD TIPSLSNVVE  60
   61 SQTIPEEDST SYLNRLEEAF CRDFRCCGQT LEDLHQLIHH YEEQHAVLAT DSAVPQEYSL 120
  121 DSNNAAQSNH SHIQALKQRE RIRMHDLADQ LGTSEISDNS AVLPFAFPAN GGAPGPYRVS 180
  181 VVVPAAAAAA AAAASSDMSS DEASSQAETT GTPKKMPESL VMDASSPLSD MSMSIDVGES 240
  241 AANNVFAFNQ KDMVDSTYLP PFNYDHDVFS FAPSVASADQ FTESSMSPTP EVVSPAATNS 300
  301 AISSPFVRKS SSDLEAKPSK KQRSTPAFSH DSPLTIDYPG SNLVVVDKPY KCPVPNCDKA 360
  361 YKNQNGLKYH KLHGHCSPIT TPTPAPIPHQ GFVVENKPYR CEVCSKRYKN LNGLKYHRTH 420
  421 SHLQVSMAQA QREVQMNFMR TA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] FFAS03 1.0 Solution Structure of the zinc finger domain of Transcriptional repressor CTCF protein
    2 View Details [104..219] deduced N/A No confident structure predictions are available.
    3 View Details [220..442] PSI-BLAST 25.69897 No description for 2i13A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  4.47951889934838 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.35187767955595 bayes_pls_golite062009
  • DNA binding
    		•  4.31051339571017 bayes_pls_golite062009
  • transcription factor activity
    		•  3.28758716579796 bayes_pls_golite062009
  • binding
    		•  2.99742524370422 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.05542379535543 bayes_pls_golite062009
  • transcription activator activity
    		•  1.97757778483124 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.44763794968807 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.26862497534835 bayes_pls_golite062009
  • chromatin binding
    		•  1.26688155139311 bayes_pls_golite062009
  • transcription factor binding
    		•  1.23738346570539 bayes_pls_golite062009
  • protein binding
    		•  0.952480850696098 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.77786753211873 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.776754909146767 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.627794176881836 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.356308409912021 bayes_pls_golite062009
  • catalytic activity
    		•  0.263007611601737 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle