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Protein Overview: vps41

General Information:
Name(s) found: vps41 / SPAP27G11.05c [Sanger Pombe]
Description(s) found:
Found 15 descriptions.
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  • vacuolar protein sorting-associated protein Vps41 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 886 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    HOPS complex [ISSLink to PubMed article]
    Biological Process: vacuole organization [ISSLink to PubMed article]
    vesicle docking [ISSLink to PubMed article]
    late endosome to vacuole transport [ISSLink to PubMed article]
    vacuole fusion, non-autophagic [ISSLink to PubMed article]
    protein targeting to vacuole [ISSLink to PubMed article]
    Golgi to endosome transport [ISSLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVDESNSDS EIDSISSSDE DEEPKLIYER ITEKFQGCFM NDTISACAIS KEHFFFGSHN  60
   61 GAIYIYQKNG ILLRKMILHS ASVVDLSVDL ESENLASCSM DGKMIISNIT TRETTVHDFK 120
  121 RPLLSVAIDP YYSTRSSRQV LSGGRAGKVV LSEKGWLGNK DTVLQADCGA VYKISWYTTY 180
  181 IAWASDLGIT VYSTEFGKVL GRLEPPKRLP NDEIFPYQLF WQSESRLVIG WSDQIMIVSI 240
  241 QRSNVANELP KISLQALLEI DSIVSGVLML GFNILTLAYI ANVEDFTSAI PSQRIEGCRP 300
  301 ELRLIDSSFK ELCGDAIGLA NYSRLQPSDY HLLPDPSSNS HSFVISPNDI VYVRERNQID 360
  361 HVKYLVSKEM YAEAIDAVKK LPEIPPSLQI SELAKKYIFH LLGKGQYKEA GMVIPSLYND 420
  421 NLAEWEQWVF VFAENDHLED IADFLPTGEN HLSPLVYEMI LAQYLATDER TFNKKLHEWP 480
  481 TMLYSVSTIR NATLKKFKEN QKSSTLTESL AFLYLEDNMP IDAFHLYLKL HSELCIDLIL 540
  541 QHNLYDEARA SVLLLMLISS KGKSSDTKSA MSSMLVQHVH SFPPQEVIMQ IHSVPQFLYE 600
  601 YFCEFELMYP NSLMEYGDLK LDVFAEFDRK RFFDFLVNTQ CYSLDHAAQI CKQYNYLDEL 660
  661 VYILGRMGNN KEALMLIINE LLDIGRAIRY VKEQADRELW DDLISYSLDK PEFICTLLEN 720
  721 IGTDENARNL LSKIPPGTKL PHMKKSISKL LADHQSQVQL YQSCYKLFKN ESISMAIKYR 780
  781 EQEQSGLEFL VKGKRSKNIF LTNLVKLDNP FNSFGDEQLD YNYRKRIPMI YDLRTKKYIR 840
  841 PEDVRIDTDD VFKDDKIAYF KTRMHLKPEV QMRNKLDLLM MLYKQT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..290] PSI-BLAST 63.39794 PAF-AH Holoenzyme: Lis1/Alfa2
    2 View Details [291..357] deduced N/A No confident structure predictions are available.
    3 View Details [358..886] PSI-BLAST 85.69897 Clathrin D6 Coat

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  2.20122168933317 bayes_pls_golite062009
  • binding
    		•  1.99637157021613 bayes_pls_golite062009
  • actin binding
    		•  1.40054662654509 bayes_pls_golite062009
  • protein binding
    		•  1.21879977456466 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • tubulin binding
    		•  1.10875870970504 bayes_pls_golite062009
  • microtubule binding
    		•  1.03769395387791 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.734793983890004 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.624115832843391 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.328276176504109 bayes_pls_golite062009
  • hydrolase activity
    		•  0.28424525033024 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.282387003961579 bayes_pls_golite062009
  • dynein binding
    		•  0.180120691665679 bayes_pls_golite062009
  • structural molecule activity
    		•  0.0588151480189092 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle