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Protein Overview: usp103

General Information:
Name(s) found: usp103 / SPBP35G2.09 [Sanger Pombe]
Description(s) found:
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  • gi|7573202|emb|CAB87371.1| U1 snRNP-associated protein Usp103 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|74625357|sp|Q9P794.1|RU1C_SCHPO RecName: Full=U1 small nuclear ribonucleoprotein C; Short=U1 snRNP protein C; Short=U1-C; AltName: Full=U1 small nuclear ribonucleoprotein usp103; Short=U1 snRNP protein usp103 [NCBI NR]
  • gi|19112176|ref|NP_595384.1| U1 snRNP-associated protein Usp103 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • U1 snRNP-associated protein Usp103 [Sanger Pombe]
  • U1 small nuclear ribonucleoprotein C OS=Schizosaccharomyces pombe GN=usp103 PE=1 SV=1 [Swiss-Prot]
  • PUTATIVE U1 SNRNP-SPECIFIC C PROTEIN; U1 SNRNP COMPONENT; POSSIBLY REQUIRED FOR SPLICEOSOME ASSEMBLY: Q9P794; [pompepVF.fasta]
  • Putative u1 small nuclear ribonucleoprotein c [pompep4896]
  • |||putative U1 snRNP-specific C protein [pompepnew.fasta]
  • SPBP35G2.09 protein [4896.FASTAC]
  • |||U1 snRNP component (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative u1 small nuclear ribonucleoprotein c [Schizosaccharomyces pombe]gi|7573202|emb|CAB87371.1| SPBP35G2.09 [Schizosaccharomyces pombe] [nrdb_11152004_Chlamydomonas]
  • |||U1 snRNP component |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (Q9P794) Putative u1 small nuclear ribonucleoprotein c [pompep4896_normal_reversed]
  • |usp103|yhc1|U1 snRNP-associated protein Usp103 |Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPBP35G2.09 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBP35G2.09 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • U1 small nuclear ribonucleoprotein C OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=usp103 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 182 amino acids

    Gene Ontology:
    Cellular Component: commitment complex [ISSLink to PubMed article]
    nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    U1 snRNP [IDALink to PubMed article]
    Biological Process: nuclear mRNA 5'-splice site recognition [IC]
    nuclear mRNA splicing, via spliceosome [ISSLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    mRNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRYLCDYCQ VWLTHDSQSV RKAHNAGRAH IQNVQDYYTK VAQEEAQKQL EERASSGFLK  60
   61 KGNGSLDLPY AYAFPPKYNV FNLGCPPPPY IVSANTYMAP KGMNAMNAAA FVPMMPAVNL 120
  121 TNQVAFSAPQ TTASSNTQLT QQQQSLPQTN EHQRARTHSN ANNHFTKTHH QGQRSHQRFV 180
  181 RA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..86] PSI-BLAST 27.0 The structure of the zinc finger from the human spliceosomal protein U1C
    2 View Details [87..182] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • U1 snRNA binding
    		•  4.35911393951689 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.60566283434269 bayes_pls_golite062009
  • DNA binding
    		•  3.55661236227495 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.48507500696529 bayes_pls_golite062009
  • snRNA binding
    		•  3.38579636849163 bayes_pls_golite062009
  • RNA binding
    		•  3.1651307444578 bayes_pls_golite062009
  • transcription factor activity
    		•  2.66585743129629 bayes_pls_golite062009
  • binding
    		•  2.51459778938853 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.8286807075508 bayes_pls_golite062009
  • transcription activator activity
    		•  1.42518458564872 bayes_pls_golite062009
  • mRNA binding
    		•  1.30742677372942 bayes_pls_golite062009
  • chromatin binding
    		•  0.89589330553881 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.8936929860974 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.882178479686399 bayes_pls_golite062009
  • transcription factor binding
    		•  0.67452735768188 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.47352407708364 bayes_pls_golite062009
  • protein binding
    		•  0.308413944574415 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.26487559807277 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.240825841910931 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.0129353639725593 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle