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Protein Overview: SPBC29A3.01

General Information:
Name(s) found: SPBC29A3.01 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • heavy metal ATPase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 904 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole membrane [IDALink to PubMed article]
    integral to membrane [IEA]
    Golgi membrane [ISSLink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    Biological Process: cellular copper ion homeostasis [TASLink to PubMed article]
    transmembrane transport [RCALink to PubMed article]
    copper ion export [IC]
    intracellular copper ion transport [ISSLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    ATP binding [ICLink to PubMed article]
    copper-exporting ATPase activity [IEA]
    copper ion binding [IEA]
    copper-transporting ATPase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYTTTLSVQG MTCTSCVASI QSMLEGVEGI EQFTISLLLE RAIAVHDPSI ISPDQIAEKI  60
   61 EDCGFDASVI SSTEGEHGVM ANYLLLSPMQ AEQWTKVHNH INELQGVLSV NCSSSPDAAI 120
  121 RVIYDSEITG PRSIMKEILS MGVKCTFQPV DSSTSRILSL QRGSQIRVWK IRFIISISFS 180
  181 LAVMFLPQIF DSCDSMRAAF LVPHYFGICA GHIISLVLSL PVQFGVGRVY YSAAYHALKR 240
  241 GTANMDVLVS LGSTVAFAAS IFFMILYSAR HADNPAPIFF DTADMLLTFV TLGRYLESKA 300
  301 KGSTSAALSQ LLSLAPSSAT IIEDNEQIEI LADLIERGDL ILVKPGEIIP VDGTVVEGSS 360
  361 YVDESSVSGE PVPVHKTIDD ELLSGTANGN GRLLVKATKS PRESQLAVIV DLVQRAQISH 420
  421 APIQQFADRV AGIFVPVIVA LSISTFTFWF LFTKYSSKYP SVFDDPMGKF AVCLKLTISV 480
  481 VVVACPCALG LSTPTAVMVG TGVGALNGII IKGGEILERL NQVDTVVFDK TGTLTVGKLS 540
  541 VTDISIVDNL EELLDIPKNI FWAFVKASES SSEHPIGKAI TEKASEFTDV SEIGIESFNA 600
  601 VPGEGVDVVL RWKERTFHAL LGNSLLLEHN NVSIPDDFDS KLKLSSSSGL TCVRIAIDGQ 660
  661 FVGFLGCMDQ VRPDSYQTVS ALKQLGKKVC LLTGDQKATA RRVAQGLEID FSDVYAEAVP 720
  721 SQKAEIIQKL KDQKHCVAMV GDGINDSPSL VLADVGIAPI NGSGIALESA DVILVRKGVL 780
  781 LDTAVSFDLS RVIVKRIKMN LVWACIYNFV MIPIAMGFFL PWGIYLNPMW ASAAMMFSSL 840
  841 SVLASSLLLR RWKKPKSLIF SEADDVETES STNSSVLQKV YTATRSIFGR NKSSNKYQPV 900
  901 ANEV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..160] PSI-BLAST 27.522879 Structure characterization of the water soluble region of P-type ATPase CopA from Bacillus subtilis
    2 View Details [161..904] PSI-BLAST 108.0 Proton ATPase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • copper chaperone activity
    		•  9.82063669832995 bayes_pls_golite062009
  • copper-dependent protein binding
    		•  9.4886676850819 bayes_pls_golite062009
  • metallochaperone activity
    		•  8.74818422646376 bayes_pls_golite062009
  • superoxide dismutase copper chaperone activity
    		•  7.67724993505658 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  6.91184156399207 bayes_pls_golite062009
  • copper ion binding
    		•  5.41725082570189 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  5.4007166857771 bayes_pls_golite062009
  • copper-exporting ATPase activity
    		•  5.04749761961029 bayes_pls_golite062009
  • copper-transporting ATPase activity
    		•  5.03252922496602 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  4.79570221435856 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.61622753861072 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.52484959112186 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.12792340516867 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  4.10264569844449 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  3.70964017127302 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
    		•  3.27250923701445 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  2.98847682261773 bayes_pls_golite062009
  • metal ion binding
    		•  2.69806984896689 bayes_pls_golite062009
  • cation binding
    		•  2.69806984896689 bayes_pls_golite062009
  • ion binding
    		•  2.69078950610234 bayes_pls_golite062009
  • transition metal ion binding
    		•  2.52520930681159 bayes_pls_golite062009
  • transporter activity
    		•  2.43435890488191 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.32163502360862 bayes_pls_golite062009
  • binding
    		•  2.31155280022787 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.28845421748925 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  1.62116507842838 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  1.61680623728503 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  1.59572740343301 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  1.5925429451548 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  1.59219836319916 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.53883152283038 bayes_pls_golite062009
  • hydrolase activity
    		•  1.26149508477113 bayes_pls_golite062009
  • ATPase activity
    		•  1.12732384636594 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.1123150216263 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.04872000948037 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.03270166246194 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.02977205960797 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.02520458852568 bayes_pls_golite062009
  • protein binding
    		•  0.889287086236279 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  0.75722873989123 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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