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Protein Overview: SPBC17A3.04c

General Information:
Name(s) found: SPBC17A3.04c [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • methionine-tRNA ligase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 782 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: methionyl-tRNA aminoacylation [ICLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    methionine-tRNA ligase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATYKVQIPA SFKTSYSFAE SLKVSIAISA FSVKVPCEGA ANCNSVRLVN SKEPEKYVSD  60
   61 ANAIVSFLYW KQEEDLFNSF ISSKLSILDW EALQFTPKAY TAKTKEDFAY LLSQLETIFK 120
  121 ENEILNEFTP VEVALASDIY FCVLNGAPVR EYPLLSAWYL KIEKQKPFVQ ALKLTFEKTL 180
  181 GQPAVTSTEK IPVSETTRNV NSQHLMRERV PGEKILPKSN ERNILITSAL PYVNNVPHLG 240
  241 NIVGSTLSAD VFARYHRARN HNTLYICGTD EYGTATETKA LEEGVSPKEL CDKYHALHKE 300
  301 VYDWFEIDFD HFGRTTTPKQ TGIAQHIFTK LYNNDYMAID TMTQLYCEVH QGYLADRYVE 360
  361 GTCPKCGYDD ARGDQCDGCG GLLNAFELID PKCKLDRATP VKRETKHVFL SLDKLQPAVE 420
  421 SWAMQSAVEG KWSNNGRSIT ESWLKEGLRP RCITRDLKWG TPVPLEEFKG KVLYVWFDAT 480
  481 IGYISITANY TDEWEKWWRN PEQVKLYQFM GKDNVPFHTV IFPSSLLGTG EKWTMLHHIN 540
  541 TTDYLNYETG KFSKSRGVGV FGNTAQDIGL SPSVWRYYLL SSRPETSDTM FTWKEFITRH 600
  601 NSELLANLGN FVNRTLKFTT AKYNGLVPHY LTDPSVGAGK LKADFVKDVN ALLAKYNAAL 660
  661 EASKLREGLR LAMEISARGN QYLQDNRIDN KCYLYERQKC ADAIGYALNL IYLLAAIFYP 720
  721 YMPSTSTSIY KQLNAPAAAI PDTWELCLLP GHRIGEPEYL FTRIDESMEE EWRSKYGGNG 780
  781 SN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..189] PSI-BLAST 21.522879 STRUCTURE OF GLUTATHIONE S-TRANSFERASE III IN APO FORM
    2 View Details [190..782] PSI-BLAST 110.0 Methionyl-tRNA synthetase from Pyrococcus abyssi

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity
    		•  1.71351657881838 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.605488421122121 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.46030380837916 bayes_pls_golite062009
  • binding
    		•  0.235855919597681 bayes_pls_golite062009
  • DNA binding
    		•  0.175092771820973 bayes_pls_golite062009
    2
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  5.54691369460949 bayes_pls_golite062009
  • isoleucine-tRNA ligase activity
    		•  3.76808520367507 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.50161401062914 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.06535308346284 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.449504767632354 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009
  • binding
    		•  0.090743795600025 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle