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Protein Overview: rfp2

General Information:
Name(s) found: rfp2 / SPAC343.18 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • ubiquitin-protein ligase E3 Rfp2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 205 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    SUMO-targeted ubiquitin ligase complex [IPILink to PubMed article]
    Biological Process: DNA repair [IGILink to PubMed article]
    negative regulation of protein sumoylation [IGILink to PubMed article][IMPLink to PubMed article]
    response to DNA damage stimulus [IGILink to PubMed article]
    regulation of mitotic cell cycle [IGILink to PubMed article]
    protein ubiquitination [RCALink to PubMed article]
    Molecular Function: [NOT]ubiquitin-protein ligase activity [IDALink to PubMed articleLink to PubMed article]
    zinc ion binding [ISSLink to PubMed article]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLHGLELPG RDQRLSPEVI DLTEDIEDDG ADVSEVTLLD LTRIPEFQPR RRIRTSRNHL  60
   61 DANLSNVPTI NSIPSPVTRP PVAVGGGIFY GARRTRNRSQ TQRRTLLENG FRNSRKKAQD 120
  121 SSNSIAERVS PPPGFCYDVH PHNNIACAKC GNELVSDEKK SIFAAKCGHL FCSTCAKELR 180
  181 KKTVPCPVQH CRKRITKKFI FPLYL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..83] MSA 1.197995 View MSA. No confident structure predictions are available.
    2 View Details [84..205] PSI-BLAST 9.69897 RAG1 DIMERIZATION DOMAIN

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  10.0460587929138 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  9.83708325747487 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  8.99384576623969 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  7.6988425139962 bayes_pls_golite062009
  • ligase activity
    		•  3.92677358871643 bayes_pls_golite062009
  • binding
    		•  2.78710909602478 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.93290256907934 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.65245433674494 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  1.64302727579554 bayes_pls_golite062009
  • protein binding
    		•  1.5975811408548 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.40546445536977 bayes_pls_golite062009
  • DNA binding
    		•  1.36987440722489 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  1.2126425713931 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  1.03469202541773 bayes_pls_golite062009
  • transcription factor binding
    		•  0.87358980288412 bayes_pls_golite062009
  • transcription factor activity
    		•  0.679771179415046 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.50197530717959 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  0.265769062717221 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle