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Protein Overview: SPCC1223.07c

General Information:
Name(s) found: SPCC1223.07c [Sanger Pombe]
Description(s) found:
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  • pir||T40867 aspartate-tRNA ligase (EC 6.1.1.12) [similarity] - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74676078|sp|O74407.1|SYDC_SCHPO RecName: Full=Aspartyl-tRNA synthetase, cytoplasmic; AltName: Full=Aspartate--tRNA ligase; Short=AspRS [NCBI NR]
  • gi|3618213|emb|CAA20876.1| cytoplasmic aspartate-tRNA ligase Drs1 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19075852|ref|NP_588352.1| aspartate-tRNA ligase (predicted) [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • aspartate-tRNA ligase [Sanger Pombe]
  • Aspartyl-tRNA synthetase, cytoplasmic OS=Schizosaccharomyces pombe GN=dps1 PE=1 SV=1 [Swiss-Prot]
  • ASPARTYL-TRNA SYNTHETASE, CYTOPLASMIC: O74407; [pompepVF.fasta]
  • Aspartyl-tRNA synthetase, cytoplasmic [pompep4896]
  • |||aspartyl-tRNA synthetase, cytoplasmic [pompepnew.fasta]
  • SPCC1223.07c protein [4896.FASTAC]
  • |||aspartate-tRNA ligase (predicted)|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • aspartyl-trna synthetase, cytoplasmic [Schizosaccharomyces pombe]gi|3618213|emb|CAA20876.1| SPCC1223.07c [Schizosaccharomyces pombe]gi|7490128|pir||T40867 aspartate-tRNA ligase (EC 6.1.1.12) [similarity] - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||aspartate-tRNA ligase |Schizosaccharomyces pombe|chr 3|||Manual [pompep2242005.fasta]
  • (O74407) Aspartyl-tRNA synthetase, cytoplasmic [pompep4896_normal_reversed]
  • |drs1||cytoplasmic aspartate-tRNA ligase Drs1 |Schizosaccharomyces pombe|chr 3|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPCC1223.07c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPCC1223.07c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • aspartate-tRNA ligase (predicted) [Schizosaccharomyces pombe 972h-] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Aspartate--tRNA ligase, cytoplasmic OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dps1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 580 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: aspartyl-tRNA aminoacylation [ICLink to PubMed article]
    Molecular Function: ATP binding [ICLink to PubMed article]
    aspartate-tRNA ligase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEMEKQVEN LSLEAKNEKP KEVILGEDGK PLSKKALKKL EKEREKEQKR KEREAREAEE  60
   61 KKKREANEID YSAGKYGDLP LNRSTARPGR TYTQISDISA KNDGQTVLLR ARVYTSRLQG 120
  121 NKMCFFSLRQ KYDTIQALAV VNKDTISKQM VKWCGSISLE SIVLVEGIVK KSPEIIKSAT 180
  181 VQDAEIHISS IYVISPIKKN LPFLVEDAGR SEEQIRESEE NAAEGDSKFV RVNLDTRLDN 240
  241 RVLDLRTPTN QAIFDIQAGI CQAFREFLLS NSFNEIHTPK MSGASSEGGS NVFKIQYFKT 300
  301 DGFLSQSPQL YKQMLIAADR ERVFEIGPVF RAEDSNTYRH MTEFTGLDLE MAFNEHYHEV 360
  361 MEFIEKLFLY IFKTIREKYA KQVAVVRQQY PSEDFILPDA DRIRFHFKDA VKLLKEAGYR 420
  421 KQLVPGQKVP EDEEFHYCED PEFDDFSTPE ERALGQIVRE KYHTDFYVID KYPSSVRPFY 480
  481 TMPDPEDPRY SNSYDFFMKG QEIMSGAQRI HDPELLVERM KALGVSPDVG LQQYIDAFAI 540
  541 GCPPHAGGGI GLERVVMFYL NLPNIRLASS FPRDPKRLLP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..580] PSI-BLAST 123.0 Aspartyl-tRNA synthetase (AspRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • lysine-tRNA ligase activity
    		•  11.0047124677093 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.89468709683036 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.89468709683036 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.88410036819636 bayes_pls_golite062009
  • ligase activity
    		•  6.92073480193262 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  5.29805946490109 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  3.80084837437429 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  3.4145644216516 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.90150581291897 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  2.61548498770105 bayes_pls_golite062009
  • structural molecule activity
    		•  2.54582212334303 bayes_pls_golite062009
  • proline-tRNA ligase activity
    		•  2.52223115725965 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  2.18642354927 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  2.07594942154162 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  1.82594054955281 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  1.72215103383322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.67362693618722 bayes_pls_golite062009
  • binding
    		•  1.54403712698597 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.48056625237411 bayes_pls_golite062009
  • DNA binding
    		•  1.44496421928708 bayes_pls_golite062009
  • translation initiation factor activity
    		•  1.27539679024898 bayes_pls_golite062009
  • transcription factor activity
    		•  0.825973629967327 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.77755643935497 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.702449673647117 bayes_pls_golite062009
  • nuclease activity
    		•  0.29926900436997 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle