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Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of pyrophosphate and AMP. Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate, to form aminoacyl-tRNA or a related compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: phenylalanine-tRNA ligase activity
Acc: GO:0004826
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).
Synonyms:
  • L-phenylalanyl-tRNA synthetase activity
  • phenylalanyl-tRNA synthetase activity
  • phenylalanine translase activity
  • phenylalanyl-transfer RNA ligase activity
  • phenylalanyl-transfer ribonucleate synthetase activity
  • phenylalanyl-transfer RNA synthetase activity
  • phenylalanine-tRNA synthetase activity
  • L-phenylalanine:tRNAPhe ligase (AMP-forming) activity
  • phenylalanyl-tRNA ligase activity
Proteins in PDR annotated with:
   This term: 67 [Search]
   Term or descendants: 67 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004826 - phenylalanine-tRNA ligase activity (interactive image map)

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