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Protein Overview: SPAC12B10.13

General Information:
Name(s) found: SPAC12B10.13 [Sanger Pombe]
Description(s) found:
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  • gi|7490267|pir||T37580 conserved hypothetical protein SPAC12B10.13 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19115557|ref|NP_594645.1| CTLH domain [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1723555|sp|Q10446.1|YDED_SCHPO RecName: Full=Uncharacterized protein C12B10.13 [NCBI NR]
  • gi|1262426|emb|CAA94703.1| CTLH domain [Schizosaccharomyces pombe] [NCBI NR]
  • CTLH domain [Sanger Pombe]
  • Uncharacterized protein C12B10.13 OS=Schizosaccharomyces pombe GN=SPAC12B10.13 PE=2 SV=1 [Swiss-Prot]
  • CONSERVED PROTEIN; CONTAINS PFAM-B_8841; SIMILAR TO HUMAN BA305P22.1; ARABIDOPSIS F11P17.12 AND T30A10.60; DROSOPHILLA CG6617 AND CG18467; NO APPARENT S. CEREVISIAE ORTHOLOG: Q10446; [pompepVF.fasta]
  • CONSERVED HYPOTHETICAL PROTEIN; CONTAINS PFAM-B_8841; SIMILARITY TO HUMAN BA305P22.1; ARABIDOPSIS F11P17.12 AND T30A10.60; DROSOPHILLA CG6617 AND CG18467: Q10446; [pompepV13]
  • Hypothetical protein C12B10.13 in chromosome I [pompep4896]
  • |||conserved protein [pompepnew.fasta]
  • |||conserved protein|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • conserved hypothetical protein. [Schizosaccharomyces pombe]gi|1262426|emb|CAA94703.1| SPAC12B10.13 [Schizosaccharomyces pombe]gi|1723555|sp|Q10446|YDED_SCHPO Hypothetical protein C12B10.13 in chromosome Igi|7490267|pir||T37580 conserved hypothetical pr [nrdb_11152004_Chlamydomonas]
  • |||conserved eukaryotic protein|Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (Q10446) Hypothetical protein C12B10.13 in chromosome I [pompep4896_normal_reversed]
  • |||proteasome-dependent catabolite inactivation protein, ubiquitin ligase complex subunit |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC12B10.13 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC12B10.13 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |||CTLH domain|Schizosaccharomyces pombe|chr 1|||Manual [spombe-190209-contam.fasta]
  • Uncharacterized protein C12B10.13 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC12B10.13 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 240 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    GID complex [ISS]
    Biological Process: proteasomal ubiquitin-dependent protein catabolic process [ISS]
    negative regulation of gluconeogenesis [ISSLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGTSSLDIS MSGSSSSDAE QWEKQTKSVH IDNSDVNSLI LDYLVIQGDE EAAKTFAEEA  60
   61 QITDYYIPPY VKERLEICEL IKSGSINSAI CKLNELEPEI LDTNSELLFE LLRLRLLELI 120
  121 REVVEEKDTS DLAVERCLNF AHENLAPLAP SNQKFLNSLE LTMSLLCFPP SSYSPALKNV 180
  181 LNYSQRERVA NLANVSILKS QGLSNESRLL SLVNFERWCE KEAQRNSIEV QKFVPKASIK 240
  241

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..63] MSA 1.186996 View MSA. No confident structure predictions are available.
    2 View Details [64..240] FFAS03 1.09 No description for 2j4bA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  3.81930570117236 bayes_pls_golite062009
  • binding
    		•  2.50754937797601 bayes_pls_golite062009
  • DNA binding
    		•  2.2601527514671 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.22506782572792 bayes_pls_golite062009
  • transcription factor activity
    		•  1.93807155691491 bayes_pls_golite062009
  • transcription factor binding
    		•  1.50833528351853 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.46658722943251 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.30345104384042 bayes_pls_golite062009
  • protein binding
    		•  1.23743665043851 bayes_pls_golite062009
  • transcription activator activity
    		•  0.627636504593051 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.590153013761442 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  0.469546809448975 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  0.469546809448975 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.38952182299124 bayes_pls_golite062009
  • catalytic activity
    		•  0.372934161904337 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.0154265016232722 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.79

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle