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Protein Overview: mst2

General Information:
Name(s) found: mst2 / SPAC17G8.13c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • histone acetyltransferase Mst2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 407 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    histone acetyltransferase complex [ISSLink to PubMed article]
    Biological Process: positive regulation of histone acetylation [IMPLink to PubMed article]
    regulation of meiotic cell cycle [IMPLink to PubMed article]
    negative regulation of chromatin silencing at telomere [IGILink to PubMed article][IMPLink to PubMed article]
    [NOT]telomere maintenance [IGILink to PubMed article]
    histone acetylation [TASLink to PubMed article]
    Molecular Function: histone acetyltransferase activity [NASLink to PubMed article]
    zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPATILKSTA SSKTLLIIKF DTNSSRYPFY KKHLLELNSE STFLGLLTKG QADTSITRLN  60
   61 QDDVRLFEKA KTVADRTKDV AYSFSDPILS TQLRTPPPQP TSIRYLYFGT YRIKPWYTSP 120
  121 YPEEYSCAKN LYICESCLKY MNSDHVLQRH KMKCSWSYPP GDEIYRDKNI SIFEVDGQRQ 180
  181 PIYCQNLCLL AKMFLHSKML YYDVEPFLFY VLTEFDGQEC KVIGYFSKEK RSASDYNVSC 240
  241 ILTLPIYQRR GYGVFLIDFS YLLTQVEGKL GSPEKPLSDL GLVTYRSYWK MRVAKALLEI 300
  301 TTPISINAIA KSTSMVCDDV ISTLESLSVF KYDPLKKKYV LQLKRDELEN VYKAWNIKHP 360
  361 QRVNPKLLRW TPYLGEEQIS NLLLKENILI PLPQKRLLDN SHHLDSV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] PSI-BLAST 5.154902 Solution Structure of the Tudor Domain from Mouse Hypothetical Protein Homologous to Histone Acetyltransferase
    2 View Details [83..407] PSI-BLAST 131.0 No description for 2givA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription repressor activity
    		•  4.08500855631983 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.64390820819794 bayes_pls_golite062009
  • methylated histone residue binding
    		•  3.42338304360938 bayes_pls_golite062009
  • chromatin binding
    		•  3.1924157640698 bayes_pls_golite062009
  • binding
    		•  3.06758476214113 bayes_pls_golite062009
  • protein binding
    		•  2.66728689880621 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.19167058827256 bayes_pls_golite062009
  • DNA binding
    		•  2.05514577638135 bayes_pls_golite062009
  • histone binding
    		•  2.00388175060339 bayes_pls_golite062009
  • transcription activator activity
    		•  1.46529895769882 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.10020047862576 bayes_pls_golite062009
  • general transcriptional repressor activity
    		•  0.75184432495983 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.294457188332415 bayes_pls_golite062009
  • catalytic activity
    		•  0.14067200158938 bayes_pls_golite062009
    2
    Term Confidence Notes
  • N-acetyltransferase activity
    		•  10.330867741687 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  10.2385402730839 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  10.2385402730839 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  10.2097972775096 bayes_pls_golite062009
  • acetyltransferase activity
    		•  9.5414870492393 bayes_pls_golite062009
  • acyltransferase activity
    		•  8.84144467104026 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  8.80032457938662 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  8.58458341779614 bayes_pls_golite062009
    		• 7.30820970670781 bayes_pls_golite062009
    		• 3.86052919290021 bayes_pls_golite062009
  • transferase activity
    		•  3.5778020729894 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.24760844790231 bayes_pls_golite062009
  • transcription activator activity
    		•  2.22111981353244 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.13750665291344 bayes_pls_golite062009
  • catalytic activity
    		•  1.97933499002461 bayes_pls_golite062009
  • myristoyltransferase activity
    		•  1.56556272138444 bayes_pls_golite062009
  • glycylpeptide N-tetradecanoyltransferase activity
    		•  1.56556272138444 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.31507488567214 bayes_pls_golite062009
  • binding
    		•  1.22537494136129 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.2180007740195 bayes_pls_golite062009
  • transcription factor binding
    		•  1.13174003342838 bayes_pls_golite062009
  • protein binding
    		•  1.12627968510377 bayes_pls_golite062009
  • H3 histone acetyltransferase activity
    		•  0.710926740598251 bayes_pls_golite062009
  • histone binding
    		•  0.582104626133107 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.483579890542134 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.31196049232138 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle