Protein Overview: SPBC106.12c

General Information:
Name(s) found:	SPBC106.12c [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	pir\|\|T39269 probable RNA binding protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR] gi\|5817278\|emb\|CAB53728.1\| THO complex subunit (predicted) [Schizosaccharomyces pombe] [NCBI NR] gi\|19111953\|ref\|NP_595161.1\| THO complex subunit (predicted) [Schizosaccharomyces pombe 972h-] [NCBI NR] gi\|12230839\|sp\|Q9URV0.1\|YBLC_SCHPO RecName: Full=Uncharacterized RNA-binding protein C106.12c [NCBI NR] THO complex subunit [Sanger Pombe] Uncharacterized RNA-binding protein C106.12c OS=Schizosaccharomyces pombe GN=SPBC106.12c PE=2 SV=1 [Swiss-Prot] RRM TYPE RNA-BINDING PROTEIN; PUTATIVE RNA AND EXPORT FACTOR BINDING PROTEIN: Q9URV0; [pompepVF.fasta] RRM TYPE RNA BINDING PROTEIN; PUTATIVE RNA AND EXPORT FACTOR BINDING PROTEIN: Q9URV0; [pompepV13] Hypothetical RNA-binding protein C106.12c in chromosome II [pompep4896] \|\|\|RNA-binding protein [pompepnew.fasta] \|\|\|RNA-binding protein\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pombe041504.fasta] RNA-binding protein; rrm RNA recognition motif; no apparent S. cerevisiae ortholog [Schizosaccharomyces pombe]gi\|19111953\|ref\|NP_595161.1\| putative RNA binding protein [Schizosaccharomyces pombe]gi\|12230839\|sp\|Q9URV0\|YBLC_SCHPO Hypothetical RNA-binding [nrdb_11152004_Chlamydomonas] (Q9URV0) Hypothetical RNA-binding protein C106.12c in chromosome II [pompep4896_normal_reversed] \|\|\|THO complex subunit \|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] SPBC106.12c [Schizosaccharomyces pombe] [nr-271106-contam.fasta] hypothetical protein SPBC106.12c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] Uncharacterized RNA-binding protein C106.12c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC106.12c PE=3 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	274 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] THO complex [ISS] nucleolus [IDA]
Biological Process:	mRNA export from nucleus [ISS] nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [ISS] regulation of RNA elongation from RNA polymerase II promoter [ISS] mRNA processing [ISS]
Molecular Function:	RNA binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLEKSLDEI INERTNGFDH KHSRRRGSQN RISKKSRLTY KFKRASKEHN SSPDDGPWQH  60
   61 DLDQEQDAHP RTTHLQKRQH SENRFGVRVE NLHYQVLEKD VLSLFENFHP IRVIMNYDRA 120
  121 GRSEGSCDVY FETSQDAEDA QKTLQSTNLK GSEIQISKKS PPSLFDRISD MPHSARKPSR 180
  181 SSRSNRGFNR SSKKDDRSFR SSSKKSSNNS ISHEDLDKEL DEYAMSFHAA STVSSHSSQD 240
  241 FTPSIANAHE KNEPVAPSKD SNLTEEMDLQ MEAV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
RNA binding	5.15097136329571	bayes_pls_golite062009
nucleic acid binding	4.92126426323641	bayes_pls_golite062009
mRNA binding	4.05281507540116	bayes_pls_golite062009
binding	3.64400841800969	bayes_pls_golite062009
	3.4479220904723	bayes_pls_golite062009
transcription regulator activity	2.18211199677674	bayes_pls_golite062009
DNA binding	1.98418556946403	bayes_pls_golite062009
single-stranded RNA binding	1.46469774223879	bayes_pls_golite062009
poly-pyrimidine tract binding	1.36691748240059	bayes_pls_golite062009
protein binding	1.12215421354121	bayes_pls_golite062009
transcription factor activity	1.07843408116687	bayes_pls_golite062009
transcription elongation regulator activity	0.961194066054671	bayes_pls_golite062009
snRNA binding	0.73428616955527	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.632534695085793	bayes_pls_golite062009
transporter activity	0.628672636801176	bayes_pls_golite062009
mRNA 3'-UTR binding	0.591700155096213	bayes_pls_golite062009
hydrolase activity	0.520121701073354	bayes_pls_golite062009
transmembrane transporter activity	0.505106991526286	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.440554367505651	bayes_pls_golite062009
sequence-specific DNA binding	0.383589644462932	bayes_pls_golite062009
structural molecule activity	0.187199936070111	bayes_pls_golite062009
substrate-specific transporter activity	0.182749906784328	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.096231856558874	bayes_pls_golite062009
pyrophosphatase activity	0.059732432409948	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.0510390778764699	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.0484248928275733	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..173]	PSI-BLAST	33.09691	Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
2	View Details	[174..274]	PSI-BLAST	13.0	Polypyrimidine tract-binding protein

Protein Overview: SPBC106.12c

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: