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View Structure Prediction Details

Protein: SPBC106.12c
Organism: Schizosaccharomyces pombe
Length: 274 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC106.12c.

Description E-value Query
Range
Subject
Range
gi|76633747 - gi|76633747|ref|XP_881817.1| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...
180.0 [0..3] [253..106]
gi|73976777 - gi|73976777|ref|XP_857296.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
179.0 [0..3] [253..106]

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Predicted Domain #1
Region A:
Residues: [1-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLEKSLDEI INERTNGFDH KHSRRRGSQN RISKKSRLTY KFKRASKEHN SSPDDGPWQH  60
   61 DLDQEQDAHP RTTHLQKRQH SENRFGVRVE NLHYQVLEKD VLSLFENFHP IRVIMNYDRA 120
  121 GRSEGSCDVY FETSQDAEDA QKTLQSTNLK GSEIQISKKS PPSLFDRISD MPH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.09691
Match: 1po6A
Description: Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.15097136329571 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
mRNA binding 4.05281507540116 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
3.4479220904723 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.98418556946403 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
poly-pyrimidine tract binding 1.36691748240059 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 1.07843408116687 bayes_pls_golite062009
transcription elongation regulator activity 0.961194066054671 bayes_pls_golite062009
snRNA binding 0.73428616955527 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.632534695085793 bayes_pls_golite062009
transporter activity 0.628672636801176 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
hydrolase activity 0.520121701073354 bayes_pls_golite062009
transmembrane transporter activity 0.505106991526286 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.440554367505651 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009
structural molecule activity 0.187199936070111 bayes_pls_golite062009
substrate-specific transporter activity 0.182749906784328 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.096231856558874 bayes_pls_golite062009
pyrophosphatase activity 0.059732432409948 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0510390778764699 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0484248928275733 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [174-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SARKPSRSSR SNRGFNRSSK KDDRSFRSSS KKSSNNSISH EDLDKELDEY AMSFHAASTV  60
   61 SSHSSQDFTP SIANAHEKNE PVAPSKDSNL TEEMDLQMEA V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1qm9A
Description: Polypyrimidine tract-binding protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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