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Protein Overview: SPAC1F5.06

General Information:
Name(s) found: SPAC1F5.06 [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • heat shock protein Lhs1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 848 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum lumen [ISSLink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: cellular response to unfolded protein [ISSLink to PubMed article]
    Molecular Function: ATP binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRSVLTIIL FFSCQFWHAF ASSVLAIDYG TEWTKAALIK PGIPLEIVLT KDTRRKEQSA  60
   61 VAFKGNERIF GVDASNLATR FPAHSIRNVK ELLDTAGLES VLVQKYQSSY PAIQLVENEE 120
  121 TTSGISFVIS DEENYSLEEI IAMTMEHYIS LAEEMAHEKI TDLVLTVPPH FNELQRSILL 180
  181 EAARILNKHV LALIDDNVAV AIEYSLSRSF STDPTYNIIY DSGSGSTSAT VISFDTVEGS 240
  241 SLGKKQNITR IRALASGFTL KLSGNEINRK LIGFMKNSFY QKHGIDLSHN HRALARLEKE 300
  301 ALRVKHILSA NSEAIASIEE LADGIDFRLK ITRSVLESLC KDMEDAAVEP INKALKKANL 360
  361 TFSEINSIIL FGGASRIPFI QSTLADYVSS DKISKNVNAD EASVKGAAFY GASLTKSFRV 420
  421 KPLIVQDIIN YPYLLSLGTS EYIVALPDST PYGMQHNVTI HNVSTIGKHP SFPLSNNGEL 480
  481 IGEFTLSNIT DVEKVCACSN KNIQISFSSD RTKGILVPLS AIMTCEHGEL SSKHKLGDRV 540
  541 KSLFGSHDES GLRNNESYPI GFTYKKYGEM SDNALRLASA KLERRLQIDK SKAAHDNALN 600
  601 ELETLLYRAQ AMVDDDEFLE FANPEETKIL KNDSVESYDW LIEYGSQSPT SEVTDRYKKL 660
  661 DDTLKSISFR FDQAKQFNTS LENFKNALER AESLLTNFDV PDYPLNVYDE KDVKRVNSLR 720
  721 GTSYKKLGNQ YYNDTQWLKD NLDSHLSHTL SEDPLIKVEE LEEKAKRLQE LTYEYLRRSL 780
  781 QQPKLKAKKG ASSSSTAESK VEDETFTNDI EPTTALNSTS TQETEKSRAS VTQRPSSLQQ 840
  841 EIDDSDEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..621] PSI-BLAST 150.0 crystal structure of bovine hsc70(aa1-554)E213A/D214A mutant
    2 View Details [622..848] PSI-BLAST 24.69897 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • unfolded protein binding
    		•  4.93074236328581 bayes_pls_golite062009
  • binding
    		•  2.11855816699924 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  1.95648644394423 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.69431775343358 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  1.43110879934367 bayes_pls_golite062009
  • peptidase activity
    		•  1.4127499531612 bayes_pls_golite062009
  • transporter activity
    		•  1.2883466875237 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.16749728168925 bayes_pls_golite062009
  • structural molecule activity
    		•  1.15845050752717 bayes_pls_golite062009
  • kinase activity
    		•  1.11102445353265 bayes_pls_golite062009
  • hexokinase activity
    		•  1.02961928132432 bayes_pls_golite062009
  • protein binding
    		•  0.956664772028256 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.953663805249074 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.900931843471417 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.898645342556399 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.875671218597808 bayes_pls_golite062009
  • hydrolase activity
    		•  0.807017237368431 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.796517590178929 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.78242344952806 bayes_pls_golite062009
  • protein transporter activity
    		•  0.780308299678282 bayes_pls_golite062009
  • ATPase activity
    		•  0.687771333492666 bayes_pls_golite062009
  • myosin binding
    		•  0.607451856096 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.309839091488096 bayes_pls_golite062009
  • catalytic activity
    		•  0.296484721581333 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.227575032167565 bayes_pls_golite062009
  • protease binding
    		•  0.121259015422625 bayes_pls_golite062009
  • DNA binding
    		•  0.0569764181525874 bayes_pls_golite062009
  • chaperone binding
    		•  0.00111313452804307 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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