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Protein Overview: rgs1

General Information:
Name(s) found: rgs1 / SPAC22F3.12c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • regulator of G-protein signaling Rgs1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 481 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: negative regulation of signal transduction involved in conjugation with cellular fusion [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPALHNPSSP PPSYEAVTSY RNGNSIDSGD KRQQCSRLMK ITSNGRPYSK DFLELFSTMV  60
   61 ISTNFSRNRY RFSYVENSCT LLQLLSTLEN LQLSQVNRIK SRCGSKVLKS TTKFTIPKTA 120
  121 AKCLCNTFLN ARLLQIVNNP SARKFSNEKC LLQLTRKGYS VVSEFLQHNG HNSQAELYAS 180
  181 KWNHSAPVIV SISRFSSTDQ ILKDSSFCEM LLVRMLGSVH EIGKSKNPLL VPVYSVSSPS 240
  241 PKDSLSKVTK YQMFGIDIAE WLMCNTMLLD WSEMETVASD LLIHSYIAYE NNSETPLKFS 300
  301 YAKGVSYFLT GKGIATLGWT KNVSNNKLIN KINEVEKGST NKEILETILR KPNLQTYFFE 360
  361 FLKKNFCDEN QRFYSEVCEF NDYFSHANET NDHEAIRESF AHACGIYNCF LSSNAPNAVN 420
  421 LPSDLYEKIT NHMALAMEVE PLNEWLQLIH ILLLEAQTAV LDLMAGDSLL KFLELNGGLG 480
  481 I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..183] FFAS03 1.63 No description for 2ysrA was found.
    2 View Details [184..293] FFAS03 0.999 Solution structure of the DEP domain of human pleckstrin
    3 View Details [294..481] PSI-BLAST 47.69897 Regulator of G-protein signalling 4, RGS4

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  3.45730892915196 bayes_pls_golite062009
  • binding
    		•  3.37660003833383 bayes_pls_golite062009
  • DNA binding
    		•  3.14200456972385 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.98154337040833 bayes_pls_golite062009
  • transcription factor activity
    		•  2.53044123488453 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.13838000453063 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.21263034180893 bayes_pls_golite062009
  • transcription activator activity
    		•  1.04520012516585 bayes_pls_golite062009
  • protein binding
    		•  0.726445167461826 bayes_pls_golite062009
  • transcription factor binding
    		•  0.534573074451495 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.302243168580314 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  2.35238988967981 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.92987277493861 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.90800479999702 bayes_pls_golite062009
  • GTPase activator activity
    		•  1.87534424848905 bayes_pls_golite062009
  • enzyme activator activity
    		•  1.62073651679221 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.49796137854909 bayes_pls_golite062009
  • protein binding
    		•  1.34804002381061 bayes_pls_golite062009
  • I-SMAD binding
    		•  0.568054578050901 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle