YRC Public Data Repository - Protein Structure Prediction

Protein:	rgs1
Organism:	Schizosaccharomyces pombe
Length:	481 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rgs1.

Description	E-value	Query Range	Subject Range
gi\|46123701, gi\|... - gi\|46123701\|ref\|XP_386404.1\| hypothetical protein FG06228.1 [Gibberella zeae PH-1], gi\|42551007\|gb\|E...	552.0	[0..8]	[475..208]
FLBA_EMENI - Developmental regulator flbA OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL... FLBA_EMENI - Developmental regulator flbA OS=Emericella nidulans GN=flbA PE=2 SV=1	508.0	[0..25]	[474..206]
gi\|116196158, gi... - gi\|88180590\|gb\|EAQ88058.1\| hypothetical protein CHGG_04677 [Chaetomium globosum CBS 148.51], gi\|1161...	506.0	[0..11]	[475..152]
gi\|28924140, gi\|... - gi\|32417094\|ref\|XP_329025.1\| hypothetical protein [Neurospora crassa], gi\|28924140\|gb\|EAA33296.1\| hy... gi\|85108218 - gi\|85108218\|ref\|XP_962532.1\| hypothetical protein [Neurospora crassa OR74A]	506.0	[0..7]	[474..210]
gi\|115384554, gi... - gi\|115384554\|ref\|XP_001208824.1\| developmental regulator flbA [Aspergillus terreus NIH2624], gi\|1141...	500.0	[0..28]	[474..202]
gi\|83769832 - gi\|83769832\|dbj\|BAE59967.1\| unnamed protein product [Aspergillus oryzae] gi\|238496363, gi... - gi\|238496363\|ref\|XP_002379417.1\| developmental regulator FlbA [Aspergillus flavus NRRL3357], gi\|2206... gi\|169775003 - gi\|169775003\|ref\|XP_001821969.1\| hypothetical protein [Aspergillus oryzae RIB40]	495.0	[0..26]	[474..208]
gi\|71001540, gi\|... - gi\|71001540\|ref\|XP_755451.1\| developmental regulator FlbA [Aspergillus fumigatus Af293], gi\|66853089...	483.0	[0..28]	[474..204]
gi\|51011900 - gi\|51011900\|gb\|AAT92283.1\| CPRGS-1 [Cryphonectria parasitica]	482.0	[0..31]	[475..1]
gi\|8745527 - gi\|8745527\|gb\|AAF78951.1\|AF267870_1 putative regulator of G protein signaling Thn1; RGS [Schizophyll...	478.0	[0..25]	[475..2]
gi\|90299595, gi\|... - gi\|90299595\|gb\|EAS29226.1\| hypothetical protein CIMG_07972 [Coccidioides immitis RS], gi\|119178236\|r...	461.0	[0..2]	[474..146]

Back

Predicted Domain #1

Region A:
Residues: [1-183]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPALHNPSSP PPSYEAVTSY RNGNSIDSGD KRQQCSRLMK ITSNGRPYSK DFLELFSTMV  60
   61 ISTNFSRNRY RFSYVENSCT LLQLLSTLEN LQLSQVNRIK SRCGSKVLKS TTKFTIPKTA 120
  121 AKCLCNTFLN ARLLQIVNNP SARKFSNEKC LLQLTRKGYS VVSEFLQHNG HNSQAELYAS 180
  181 KWN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.63
Match:	2ysrA
Description:	No description for 2ysrA was found.

Predicted Domain #2

Region A:
Residues: [184-293]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSAPVIVSIS RFSSTDQILK DSSFCEMLLV RMLGSVHEIG KSKNPLLVPV YSVSSPSPKD  60
   61 SLSKVTKYQM FGIDIAEWLM CNTMLLDWSE METVASDLLI HSYIAYENNS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.999
Match:	2csoA
Description:	Solution structure of the DEP domain of human pleckstrin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.45730892915196	bayes_pls_golite062009
binding	3.37660003833383	bayes_pls_golite062009
DNA binding	3.14200456972385	bayes_pls_golite062009
nucleic acid binding	2.98154337040833	bayes_pls_golite062009
transcription factor activity	2.53044123488453	bayes_pls_golite062009
transcription repressor activity	2.13838000453063	bayes_pls_golite062009
sequence-specific DNA binding	1.21263034180893	bayes_pls_golite062009
transcription activator activity	1.04520012516585	bayes_pls_golite062009
protein binding	0.726445167461826	bayes_pls_golite062009
transcription factor binding	0.534573074451495	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.302243168580314	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [294-481]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETPLKFSYAK GVSYFLTGKG IATLGWTKNV SNNKLINKIN EVEKGSTNKE ILETILRKPN  60
   61 LQTYFFEFLK KNFCDENQRF YSEVCEFNDY FSHANETNDH EAIRESFAHA CGIYNCFLSS 120
  121 NAPNAVNLPS DLYEKITNHM ALAMEVEPLN EWLQLIHILL LEAQTAVLDL MAGDSLLKFL 180
  181 ELNGGLGI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.69897
Match:	1agrE
Description:	Regulator of G-protein signalling 4, RGS4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.35238988967981	bayes_pls_golite062009
GTPase regulator activity	1.92987277493861	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	1.90800479999702	bayes_pls_golite062009
GTPase activator activity	1.87534424848905	bayes_pls_golite062009
enzyme activator activity	1.62073651679221	bayes_pls_golite062009
enzyme regulator activity	1.49796137854909	bayes_pls_golite062009
protein binding	1.34804002381061	bayes_pls_golite062009
I-SMAD binding	0.568054578050901	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: