YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: smc5

General Information:
Name(s) found: smc5 / SPAC14C4.02c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
SHOW ALL
  • Smc5-6 complex SMC subunit Smc5 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1065 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    cell division site [IDALink to PubMed article]
    Smc5-Smc6 complex [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    spindle [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: replication fork protection [ICLink to PubMed article]
    double-strand break repair via homologous recombination [TASLink to PubMed article]
    Molecular Function: ATP binding [ISSLink to PubMed article]
    protein binding [IPILink to PubMed articleLink to PubMed article]
    protein heterodimerization activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILTRESYAL GSIVRIKLVN FVTYDYCELF PGPYLNLIIG PNGTGKSTIV SAICIGLGWP  60
   61 PKLLGRAKEA REFIKYGKNT ATIEIEMKYR DDETVTITRQ ISQDKSSSFS INREACATSS 120
  121 ITSLMDTFNV QLNNLCHFLP QDRVAEFAQL DPYSRLMETE RAIDHEGLLP AHEKLIDLRK 180
  181 REREILQNKN QGQSTLNSLK DRQQALEKEV NIFKEREKIK SYIEMLGLAK MLVIYREKTN 240
  241 VFNQLRADKK KLKKDLKDLV EEFQPILDKG EELRSDLKLK DDTFNDYSSA SMELNTSNLR 300
  301 ARASFSNFME NEKKLYEKVN TNRTLLRNAN LTLNEAQQSV KSLTERQGPR PSDNGVQDLQ 360
  361 EKMQEVNAEK LQHENEKLES SHELGSIRTL KAQKLIDLDN IKRELSYYND ATKRKLDFMS 420
  421 SAPGWEDAYQ TYQLLKEYES AFEAPAYGPI YMNLKCKEKG FAALIEGFFR TDTFRTFIMS 480
  481 NYNDYLKLMD LITSKTKYTP TIREFSSERK KKIEDFEPPC SREKLQSFGF DGYVIDFLEG 540
  541 PEVVLVALCH MLKIHQIPIA KRELPPASVN ALNNFRLANG DPVLKTYLAG SSIHLVFRSA 600
  601 YGDREITRRT DPLPSRSIYF SENVEMDLVK RKEEQLNAQL SQLENLQNEE RKLQEKVNEH 660
  661 ESLLSRTNDI LSTLRKERDE KLIPIHEWQQ LQERIEHQTL LLRQREKVPE QFAAEIEKNE 720
  721 DIRKENFEAL MNSVLKVKEN SIKATNNFEK MLGSRLNVIE AKYKLEKHEM DANQVNARLT 780
  781 EVQDRLKDIT DKLASAREDA MSLYGSVVDS LQTQSSDRQT AITELNEEFA TSSEVDNKIS 840
  841 IEETKLKFMN VNSYVMEQYD ARKKEIEELE SKMSDFDQSV EELQDEMNSI KEDWVSKLEE 900
  901 NVQCISDRFS KGMSGMGYAG EVRLGKSDDY DKWYIDILVQ FREEEGLQKL TGQRQSGGER 960
  961 SVSTIMYLLS LQGLAIAPFR IVDEINQGMD PRNERVVHRH IVNSVCDNAV SQYFLVTPKL1020
 1021 LPDLTYHRNL KVLCICNGAW LPATFRTSLS TYFEKLKKSA LISSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..273] PSI-BLAST 21.0 Sc Smc1hd:Scc1-C complex, ATPgS
    2 View Details [274..771] FFAS03 1.69 Tropomyosin
    3 View Details [772..1065] PSI-BLAST 4.045757 No description for 2iw3A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA clamp loader activity
    		•  3.22518920754305 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  3.19273435123154 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  2.72462789867829 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • motor activity
    		•  2.40267948113603 bayes_pls_golite062009
  • microtubule motor activity
    		•  2.37639635793291 bayes_pls_golite062009
  • DNA helicase activity
    		•  2.2817164193758 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.21184938313192 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.13284212711072 bayes_pls_golite062009
  • DNA binding
    		•  1.94055378599526 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.88455339138556 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.83584389083042 bayes_pls_golite062009
  • bubble DNA binding
    		•  1.70168298920956 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.50574672650697 bayes_pls_golite062009
  • helicase activity
    		•  1.16085745407703 bayes_pls_golite062009
  • tubulin binding
    		•  1.01673904002272 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.971476020912368 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.928091843881235 bayes_pls_golite062009
  • microtubule binding
    		•  0.902404986889887 bayes_pls_golite062009
  • actin binding
    		•  0.875514430441177 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.720649395550746 bayes_pls_golite062009
  • transcription factor activity
    		•  0.697256579145077 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.677612020025357 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.59513742813869 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.59513742813869 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.58862275163252 bayes_pls_golite062009
  • centromeric DNA binding
    		•  0.322818640526369 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.26523838851913 bayes_pls_golite062009
  • four-way junction helicase activity
    		•  0.26252931460003 bayes_pls_golite062009
  • exodeoxyribonuclease V activity
    		•  0.185603938981231 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.147579541298736 bayes_pls_golite062009
  • nucleotide binding
    		•  0.114848452385726 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.113504049290503 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.111293884322157 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.10713474095071 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0916519414118148 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0915913646217636 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.089234257580272 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle