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Protein Overview: prr1

General Information:
Name(s) found: prr1 / SPAC8C9.14 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • transcription factor Prr1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 539 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: two-component signal transduction system (phosphorelay) [IEA]
    conjugation with cellular fusion [IGILink to PubMed article]
    regulation of two-component signal transduction system (phosphorelay) [ICLink to PubMed article]
    regulation of transcription, DNA-dependent [IMPLink to PubMed article]
    cellular response to oxidative stress [IGILink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [RCALink to PubMed article]
    Molecular Function: DNA binding [IEA]
    transcription factor activity [IEA]
    specific RNA polymerase II transcription factor activity [RCALink to PubMed article]
    two-component response regulator activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSSNGSSDF VRKLFNMLEE PEYRHILRWS DSGDSFIVLD TNEFTKTILP RHFKHSNFAS  60
   61 FVRQLNKYDF HKVRHEEGAP SIYGEGAWEF RHDDFQLHHK DLLDNIKRKA PSKRNLANEN 120
  121 TAPVIENLKQ QVDSILDFQK LLDRNLSGLA TSYQTILLKM FELKRGIESR DLLMSSIISY 180
  181 LCDLEGSTQR QANPGAMFVP SHPLQELLNA YQALAKGQVA TTSPQQIPNQ IQQASAATTA 240
  241 SSKMTVDTNL GTAQPSLYNT PSSDYELANQ EKPADSMASA ASLNTPLSSN DHSLNPHAHG 300
  301 SYPMYEKFQP IQHPNPGSFT THLDSNASMA KSFSQISNDS LAKASSVATS MSQMGAAVPT 360
  361 TGLWKRQPRI LLVEDDELSR RMTIKFLTSF DCQVDVAVDG IGAVNKANAG GFDLILMDFI 420
  421 LPNLDGLSVT CLIRQYDHNT PILAITSNIS MNDAVTYFNH GVTDLLVKPF TKLTLLQLLK 480
  481 KQLLNLLQAD NSINMSDVPS TKEAKDDKAP VTFYLENDAP MYPQQMLQDP IQADLQHPH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..94] PSI-BLAST 13.522879 SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR
    2 View Details [95..367] PSI-BLAST 27.221849 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
    3 View Details [368..539] PSI-BLAST 39.0 No description for 2oqrA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.55329976718261 bayes_pls_golite062009
  • DNA binding
    		•  5.08959163553491 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.99681957904233 bayes_pls_golite062009
  • transcription factor activity
    		•  4.33152142980289 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.48053910222825 bayes_pls_golite062009
  • transcription activator activity
    		•  2.37668609508629 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.22485867684613 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.70025468248325 bayes_pls_golite062009
  • transcription factor binding
    		•  0.85714789329232 bayes_pls_golite062009
  • protein binding
    		•  0.753698599635855 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.359916369552683 bayes_pls_golite062009
  • two-component response regulator activity
    		•  0.290986349914258 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.0856082199488197 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle