YRC Public Data Repository - Protein Structure Prediction

Protein:	prr1
Organism:	Schizosaccharomyces pombe
Length:	539 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prr1.

Description	E-value	Query Range	Subject Range
gi\|83646376, gi\|... - gi\|83646376\|ref\|YP_434811.1\| Signal transduction histidine kinase [Hahella chejuensis KCTC 2396], gi...	258.0	[0..47]	[496..383]
gi\|39997412, gi\|... - gi\|39997412\|ref\|NP_953363.1\| sensory box histidine kinase/response regulator [Geobacter sulfurreduce...	258.0	[0..16]	[538..351]
gi\|125973324, gi... - gi\|67876007\|ref\|ZP_00505065.1\| PAS [Clostridium thermocellum ATCC 27405], gi\|67850331\|gb\|EAM45912.1\|...	257.0	[0..37]	[496..330]
gi\|114566853, gi... - gi\|71541312\|ref\|ZP_00663086.1\| PAS [Syntrophomonas wolfei str. Goettingen], gi\|71492116\|gb\|EAO24426....	256.0	[0..10]	[499..172]
gi\|54307731, gi\|... - gi\|54307731\|ref\|YP_128751.1\| sensory box sensor histidine kinase/response regulator [Photobacterium ...	256.0	[0..10]	[532..369]
gi\|90580619, gi\|... - gi\|90580619\|ref\|ZP_01236424.1\| hypothetical sensory box sensor histidine kinase/response regulator [...	255.0	[0..69]	[534..395]
gi\|90413136, gi\|... - gi\|90413136\|ref\|ZP_01221132.1\| hypothetical sensory box sensor histidine kinase/response regulator [...	254.0	[0..10]	[532..355]
gi\|37680917, gi\|... - gi\|37680917\|ref\|NP_935526.1\| sensory box sensor histidine kinase/response regulator [Vibrio vulnific...	254.0	[0..18]	[538..375]
gi\|82945896, gi\|... - gi\|83311055\|ref\|YP_421319.1\| Signal transduction histidine kinase [Magnetospirillum magneticum AMB-1...	253.0	[0..12]	[485..40]
gi\|27365036, gi\|... - gi\|27365036\|ref\|NP_760564.1\| sensory box sensor histidine kinase/response regulator [Vibrio vulnific...	253.0	[0..18]	[538..375]

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Predicted Domain #1

Region A:
Residues: [1-94]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSSNGSSDF VRKLFNMLEE PEYRHILRWS DSGDSFIVLD TNEFTKTILP RHFKHSNFAS  60
   61 FVRQLNKYDF HKVRHEEGAP SIYGEGAWEF RHDD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.522879
Match:	1hksA
Description:	SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	5.55329976718261	bayes_pls_golite062009
DNA binding	5.08959163553491	bayes_pls_golite062009
nucleic acid binding	4.99681957904233	bayes_pls_golite062009
transcription factor activity	4.33152142980289	bayes_pls_golite062009
binding	3.52874320222492	bayes_pls_golite062009
sequence-specific DNA binding	2.48053910222825	bayes_pls_golite062009
transcription activator activity	2.37668609508629	bayes_pls_golite062009
transcription repressor activity	2.22485867684613	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.70025468248325	bayes_pls_golite062009
transcription factor binding	0.85714789329232	bayes_pls_golite062009
protein binding	0.753698599635855	bayes_pls_golite062009
structure-specific DNA binding	0.359916369552683	bayes_pls_golite062009
two-component response regulator activity	0.290986349914258	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.0856082199488197	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [95-367]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQLHHKDLLD NIKRKAPSKR NLANENTAPV IENLKQQVDS ILDFQKLLDR NLSGLATSYQ  60
   61 TILLKMFELK RGIESRDLLM SSIISYLCDL EGSTQRQANP GAMFVPSHPL QELLNAYQAL 120
  121 AKGQVATTSP QQIPNQIQQA SAATTASSKM TVDTNLGTAQ PSLYNTPSSD YELANQEKPA 180
  181 DSMASAASLN TPLSSNDHSL NPHAHGSYPM YEKFQPIQHP NPGSFTTHLD SNASMAKSFS 240
  241 QISNDSLAKA SSVATSMSQM GAAVPTTGLW KRQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.221849
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [368-539]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRILLVEDDE LSRRMTIKFL TSFDCQVDVA VDGIGAVNKA NAGGFDLILM DFILPNLDGL  60
   61 SVTCLIRQYD HNTPILAITS NISMNDAVTY FNHGVTDLLV KPFTKLTLLQ LLKKQLLNLL 120
  121 QADNSINMSD VPSTKEAKDD KAPVTFYLEN DAPMYPQQML QDPIQADLQH PH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.0
Match:	2oqrA
Description:	No description for 2oqrA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: