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Protein Overview: pabp

General Information:
Name(s) found: pabp / SPAC57A7.04c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
SHOW ALL
  • mRNA export shuttling protein [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 653 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: mRNA export from nucleus [IMPLink to PubMed article]
    regulation of translational initiation [ISS]
    Molecular Function: poly(A) RNA binding [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSTDLKKQA DAAVESDVNT NNEAVESSTK EESSNTPSTE TQPEKKAEEP EAAAEPSEST  60
   61 STPTNASSVA TPSGTAPTSA SLYVGELDPS VTEAMLFELF NSIGPVASIR VCRDAVTRRS 120
  121 LGYAYVNFHN MEDGEKALDE LNYTLIKGRP CRIMWSQRDP SLRKMGTGNV FIKNLDPAID 180
  181 NKALHDTFSA FGKILSCKVA VDELGNAKGY GFVHFDSVES ANAAIEHVNG MLLNDKKVYV 240
  241 GHHVSRRERQ SKVEALKANF TNVYIKNLDT EITEQEFSDL FGQFGEITSL SLVKDQNDKP 300
  301 RGFGFVNYAN HECAQKAVDE LNDKEYKGKK LYVGRAQKKH EREEELRKRY EQMKLEKMNK 360
  361 YQGVNLFIKN LQDEVDDERL KAEFSAFGTI TSAKIMTDEQ GKSKGFGFVC YTTPEEANKA 420
  421 VTEMNQRMLA GKPLYVALAQ RKEVRRSQLE AQIQARNQFR LQQQVAAAAG IPAVQYGATG 480
  481 PLIYGPGGYP IPAAVNGRGM PMVPGHNGPM PMYPGMPTQF PAGGPAPGYP GMNARGPVPA 540
  541 QGRPMMMPGS VPSAGPAEAE AVPAVPGMPE RFTAADLAAV PEESRKQVLG ELLYPKVFVR 600
  601 EEKLSGKITG MLLEMPNSEL LELLEDDSAL NERVNEAIGV LQEFVDQEPG FTE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..73] PSI-BLAST 18.0 CG8781 protein
    2 View Details [74..254] PSI-BLAST 50.221849 Poly(A)-binding protein
    3 View Details [255..348] PSI-BLAST 6.69897 Splicing factor U2AF 65 KDa subunit
    4 View Details [349..453] FFAS03 4.63 No description for 2f3jA was found.
    5 View Details [454..653] PSI-BLAST 32.522879 poly(A) binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • structural molecule activity
    		•  4.28696884073791 bayes_pls_golite062009
  • snRNA binding
    		•  4.06596327298973 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • translation initiation factor activity
    		•  3.27900316559423 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • U1 snRNA binding
    		•  3.02511982045347 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • DNA binding
    		•  1.98418556946403 bayes_pls_golite062009
  • U2 snRNA binding
    		•  1.34078165372485 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription factor activity
    		•  1.07843408116687 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.824614388276642 bayes_pls_golite062009
  • transporter activity
    		•  0.417047632648771 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
  • translation regulator activity
    		•  0.38120065819101 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.288804044686487 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.128616879457381 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00171911393626201 bayes_pls_golite062009
    3
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • structural molecule activity
    		•  4.28696884073791 bayes_pls_golite062009
  • snRNA binding
    		•  4.06596327298973 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • translation initiation factor activity
    		•  3.27900316559423 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • U1 snRNA binding
    		•  3.02511982045347 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • DNA binding
    		•  1.98418556946403 bayes_pls_golite062009
  • U2 snRNA binding
    		•  1.34078165372485 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription factor activity
    		•  1.07843408116687 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.824614388276642 bayes_pls_golite062009
  • transporter activity
    		•  0.417047632648771 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
  • translation regulator activity
    		•  0.38120065819101 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.288804044686487 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.128616879457381 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00171911393626201 bayes_pls_golite062009
    4 No functions predicted.
    5
    Term Confidence Notes
  • RNA binding
    		•  5.69788763665792 bayes_pls_golite062009
  • mRNA binding
    		•  5.31297072316889 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  4.51056428709072 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.78909647605682 bayes_pls_golite062009
  • eukaryotic initiation factor 4G binding
    		•  3.4111148675327 bayes_pls_golite062009
  • binding
    		•  2.76167454154417 bayes_pls_golite062009
  • poly(A) RNA binding
    		•  2.66269581586161 bayes_pls_golite062009
  • poly-purine tract binding
    		•  2.20136693536924 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.19350242454642 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.14692713780316 bayes_pls_golite062009
  • protein binding
    		•  0.856075580719879 bayes_pls_golite062009
  • ligase activity
    		•  0.38737123012383 bayes_pls_golite062009
  • catalytic activity
    		•  0.287695754348243 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.223805219849164 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle