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Protein Overview: nup124

General Information:
Name(s) found: nup124 / SPAC30D11.04c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • nucleoporin Nup124 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1159 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    nuclear pore [TASLink to PubMed article]
    Biological Process: ribosomal subunit export from nucleus [ISS]
    transposition, RNA-mediated [IMPLink to PubMed article]
    nuclear import [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPVSKNTRT SSKTVKKPYD PPQGSSRPFF TVLKRAFSSV LHPFTSGLDE KASGTASKDR  60
   61 KSGRAGTKSL LTPELTPHYL GKSPRIIRVS NRSHVRTIDG IEEKVHTNTF EPRKPKQKQD 120
  121 YTNSPTLFKR HDELSLKSLN SLHPSSALSK KLGSTSQHQI ATPKSSASLL NILRSLHDEQ 180
  181 KNTLNISSVK QDRITEANPT CEKRKPSRSP SPMLSKKKSV ARASENEPSA KQNKSFSGND 240
  241 SHKSLTDIRD KENGETEVSA KNHVPHRSSR RRRRHQRLIP IIYETLEQMD LRKPVLVNAE 300
  301 VQTDSNPGNT MFIDKQDIYH RLSTPTSRKR QTLEKGHIKA FSAVDEDLDE IFACEDDVHY 360
  361 TALPKQNPKS ERILEPIIAS PKDNTSDKGL LTKSAPTFEE LQASITPKPV KTSPNDTALT 420
  421 LANAEDNKTF EHQPLSKDTE APKSQFSSSP TKESTTRKSE VEPPSPSKEI KSSHFSVPEF 480
  481 KFEPKTEATT DKKLNVPKFE FKPTATADVQ TNRLKENEPK PTFFAQLPSK TQETPSITEN 540
  541 KPSFFSQLSP KREETEKKDN APSAPASTSG FSFGGFAPKT LEEKEETKAP TFNFSLNNAS 600
  601 STQDTTKPTL QFNFGSSFGK PTSNIFNDKK TSENGLASST VASESKPSAP ESKPSSGFGN 660
  661 TAGSSPFSFN LTKESKEVPP TNSFSFAKKG KDEANDSLSA KASTPFSFAK PNTENVTTTA 720
  721 PQFSFNFTKP NTDAKTNLLP EKTFNEEAVK QKETEKEVPP TGPKASEIKD SVSSNNAVPS 780
  781 STFNFVSPFA AVSEKTNENN IPNDTTKTNG NATKRTLEQT EDAKPFAFSF GSTTEQANKK 840
  841 ASTSNETTKP QLDTSSKTDG VTANAPFSFA SAFNAPKPST NTADGKDSAS NLTTPSPAFS 900
  901 FGNNSGVKAS SNNNPSTNSS TAPFSFGTSN KPAFSFGSAT SKTTSEGTAP AASASAPAPT 960
  961 TSAFSFGASN SSMNKEENTP MAKDAGDTAP ASGFKSGFSF GANNSPQPAS MFGTSTPAPS1020
 1021 SAFAFGNQSG TNPAAPAGFG GITNTATNNP PSTGFTFTPS NAGSTAAPMF GAGNTPNPSG1080
 1081 SINNASQAFA FGSGEPSNPA SNPPSTGFSF GAATPSAFNA SASQSPAPNG IQFNLGSSNS1140
 1141 QTNAPPGRKI AVPRSRRKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..422] FFAS03 1.03 G-protein coupled receptor kinase 2, N-terminal domain; G-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1); G-protein coupled receptor kinase 2
    2 View Details [423..511] deduced N/A No confident structure predictions are available.
    3 View Details [512..635] MSA 1.16499 View MSA. No confident structure predictions are available.
    4 View Details [636..768] deduced N/A No confident structure predictions are available.
    5 View Details [769..1002] deduced N/A No confident structure predictions are available.
    6 View Details [1003..1159] MSA 1.131996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.22428758317736 bayes_pls_golite062009
  • protein binding
    		•  1.54961752900242 bayes_pls_golite062009
  • protein kinase activity
    		•  1.31419329313343 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.20088944410496 bayes_pls_golite062009
  • transporter activity
    		•  1.14487771276691 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.06759196344598 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.04308738565528 bayes_pls_golite062009
  • receptor activity
    		•  1.02162548955804 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.994293779520251 bayes_pls_golite062009
  • kinase activity
    		•  0.989702565083208 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.833831720654728 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.724052049967156 bayes_pls_golite062009
  • Ran GTPase binding
    		•  0.709291241748316 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.695021063527918 bayes_pls_golite062009
  • signal transducer activity
    		•  0.695021063527918 bayes_pls_golite062009
  • transferase activity
    		•  0.624121946809127 bayes_pls_golite062009
  • catalytic activity
    		•  0.593995061424214 bayes_pls_golite062009
  • ATP binding
    		•  0.572345879629496 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.566982635339813 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.541384252517142 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.534108415835127 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.521108494674166 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.521107326648506 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.521095364461424 bayes_pls_golite062009
  • nucleotide binding
    		•  0.515729013116388 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.468575645137665 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  0.415062676534168 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.16568361458757 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  0.0997896740350728 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0229080352184639 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle