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Protein Overview: pmh1

General Information:
Name(s) found: pmh1 / SPBC776.18c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • transcription factor TFIIH complex subunit Pmh1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 318 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    holo TFIIH complex [TASLink to PubMed article]
    nucleotide-excision repair factor 3 complex [ISSLink to PubMed article]
    Biological Process: nucleotide-excision repair [ISSLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [ICLink to PubMed article]
    protein ubiquitination [ISSLink to PubMed article]
    regulation of cyclin-dependent protein kinase activity [IGILink to PubMed article]
    Molecular Function: ubiquitin-protein ligase activity [ISSLink to PubMed article]
    zinc ion binding [ISSLink to PubMed article]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDEGARKVD EKCPLCQADR YLNPNMKLLI NPECYHKMCE SCVDRIFTTG PAQCPTPGCN  60
   61 KILRKAKFRE QTFEDAQIER EVDVRKRISR IFNKGQQEFD SLQAYNDYLE EVEILTFNLI 120
  121 YKIDVEETEE KVKQYEKQNR DSIAANSARA AAEARILAQN EILLKRQKQE AREAAIREHQ 180
  181 KEKERREQVE QQIIFDLATS GKDPNKIIQL SDSLKKQQEN IASSVSNISR SSSILLSDVQ 240
  241 QVAEDTTPFS PLAGEKDGSK YFSYSKNTYQ DLYLEKVSHE PGRKCGFRIE DCHLRCLYEA 300
  301 FSGIDYDLES LKKLEVAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..66] PSI-BLAST 4.221849 TFIIH Mat1 subunit
    2 View Details [67..318] PSI-BLAST 4.69897 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  6.51043144330453 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  5.97121728620188 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  5.78935175140238 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.75377804653841 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  3.82459130917693 bayes_pls_golite062009
  • binding
    		•  2.78710909602478 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.72498741013971 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.32387297115017 bayes_pls_golite062009
  • DNA binding
    		•  2.00904221080834 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.98209395225978 bayes_pls_golite062009
  • protein binding
    		•  1.5975811408548 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22579085356684 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  1.2126425713931 bayes_pls_golite062009
  • transcription factor binding
    		•  1.11842175076436 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  1.03469202541773 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.90321253993065 bayes_pls_golite062009
  • ligase activity
    		•  0.63517530468004 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.50197530717959 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.384990496120483 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  0.265769062717221 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.255669498391574 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.233838999434784 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
  • transcription activator activity
    		•  0.126093965701234 bayes_pls_golite062009
  • enzyme binding
    		•  0.104373352314595 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle