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Protein Overview: krp1

General Information:
Name(s) found: krp1 / SPAC22E12.09c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • kexin [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 709 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Golgi apparatus [IDALink to PubMed article]
    cell surface [NASLink to PubMed article]
    Biological Process: proteolysis [IGILink to PubMed article]
    peptide pheromone maturation [TASLink to PubMed article]
    Molecular Function: calcium ion binding [IEA]
    serine-type endopeptidase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHPALLCGPI LAIFLQFLVS SCSPLENDDL FLVQVEPEVD PVVAAEAIGA KYVRPLLNLK  60
   61 YHHLIKLHKG SDDSVQSSIR KRGIDAGILE LERQTPRWRY KRDASESDEL LNEFSNHFGI 120
  121 SDPLFYGQWH IFNSNNPGHD LNLREVWDAG YFGENVTVAF VDDGIDFKHP DLQAAYTSLG 180
  181 SWDFNDNIAD PLPKLSDDQH GTRCAGEVAA AWNDVCGVGI APRAKVAGLR ILSAPITDAV 240
  241 ESEALNYGFQ TNHIYSCSWG PADDGRAMDA PNTATRRALM NGVLNGRNGL GSIFVFASGN 300
  301 GGHYHDNCNF DGYTNSIFSA TIGAVDAEHK IPFYSEVCAA QLVSAYSSGS HLSILTTNPE 360
  361 GTCTRSHGGT SAAAPLASAV YALALSIRPD LSWRDIQHIT VYSASPFDSP SQNAEWQKTP 420
  421 AGFQFSHHFG FGKLDASKFV EVAKDWQVVN PQTWLIAPEI NVNKSFGSVN NETITEMVSE 480
  481 FTVTKDMIEK SNFKRLEHVT VRVCIPFNRR GALEILLESP SGIRSILASE RPYDENSKGF 540
  541 LDWTFMTVQH WAEPPEGVWK LLVNDRSGGK HEGTFENWQL ALWGESENPS NTAPLPYDTL 600
  601 ELPKEMVLGI YSEPNSDLTN SSTLLSPTST SFTSYTVSAT ATPTSTSHIP IPTVLPPTQP 660
  661 VLEPSYREIV AFITFFLLFA FIFVAVIWTW ISAFWKAKAP PPLSQQEIA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..123] PSI-BLAST 45.522879 Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin
    2 View Details [124..597] PSI-BLAST 97.221849 No description for 2id4A was found.
    3 View Details [598..709] MSA 1.182995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  4.77677490610016 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.40501322467328 bayes_pls_golite062009
  • serine hydrolase activity
    		•  4.30899317351154 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  4.29545891350519 bayes_pls_golite062009
  • nerve growth factor binding
    		•  3.93556598541015 bayes_pls_golite062009
  • endopeptidase activity
    		•  3.83336601331518 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  3.71508033196614 bayes_pls_golite062009
  • neurotrophin binding
    		•  3.66310728475581 bayes_pls_golite062009
  • hydrolase activity
    		•  2.05732080397524 bayes_pls_golite062009
  • eukaryotic cell surface binding
    		•  1.50287724152407 bayes_pls_golite062009
  • binding
    		•  1.08901362883653 bayes_pls_golite062009
  • growth factor binding
    		•  0.67723819767183 bayes_pls_golite062009
  • catalytic activity
    		•  0.597535457699629 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.42083764849682 bayes_pls_golite062009
  • protein binding
    		•  0.380935140681308 bayes_pls_golite062009
  • receptor binding
    		•  0.222369968782666 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.11649614154172 bayes_pls_golite062009
  • cell surface binding
    		•  0.0917795720340502 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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