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Protein Overview: kap123

General Information:
Name(s) found: kap123 / SPBC14F5.03c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • karyopherin Kap123 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1067 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    nucleus [IDALink to PubMed article]
    nuclear membrane [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    nuclear pore [TASLink to PubMed article]
    Biological Process: nucleocytoplasmic transport [TASLink to PubMed article]
    protein targeting [RCALink to PubMed article]
    intracellular protein transport [IEA]
    Molecular Function: protein transporter activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAQFTLELT QLLFQSIAPD TTQITEATRA LETKYLKEPG SLLSLFHIMG TCENPQVRQL  60
   61 AAIEARKLCH KYWSSVDADV QNQIRSNLLD ITLKEPESIV RHAFGRVIAA LAKLDLPEGK 120
  121 WNELSAFLVQ ATMDQNDSIR EMAVYVLYSI AETVDLDNKL LLDFVNLFSQ TITDSSRTVR 180
  181 VTSVQGLGAI AEVLESDDKK LLHAYRATLP GMLLVLQDVV QVGDVDASKQ VFDVFNTFLI 240
  241 ASGAIISKAL GNIIEIITGI ANSKQVDDEI RCMALSFIIS CIRFKSRKLQ ALKLGKPLVL 300
  301 TLMEVATEET TDDIDEDCPA RLALRSIDLL STHLSPSQVF YPMFEAACAF SQSPQASYRK 360
  361 AALLSIGVAV EGSSESVAGN LPNIFPIIIN GLCDNDMDVR QAALLALSQI AVEIPTEVSK 420
  421 HHAQLLPLVF ELMSTQGVKV GKSACNCIDA LLEGLDKSEI SGYLPMLMER LVGLLEFSDT 480
  481 PDIKSCVAAA IGSAAFAAQD DFIPYFERTM ASLSQCLHTT DDDEGYELRG TVMDTLGAIA 540
  541 NAVGKQAFLP YTEQLIQLAY EGIQIDHSRL RECSFCFYAV LARVYKEEFA PFLEHIVPAL 600
  601 FKSIDQDESD ILSERIGAPT AEEISQLLDS VETNEEENDE ELEKAMGVNS AIAMEKEIAA 660
  661 DALGEICMYV GAPFTPYLEP TVEKLVACTT HFYEGVRKSA LSSLWRCATT YYKVCNVPQW 720
  721 QPGLPLKVPV PDTVKNIFEA VRKCTFDTLE EEYEKTVATD ILRNFAESIK TCGPVVLGDD 780
  781 YEKLCEVVME VLQKQHIVQA GDVFDDDFEE EDIVSNEEVD DTEQDALLID SACDVVIALA 840
  841 VALGGSFADS FKVFYPQIVK YYMSKNGNER AMAVACVGEV AGGIESAITP FTRDVFSLFM 900
  901 AALEDSEGEV RSNAAYSMGL LCQFSTEDLS SEYLNILQKL QPFFTQEVFR TALDNAIGCI 960
  961 SRLILHNQNA IPVDQVLPIV FSKLPLKEDY LENAPLYHMI LALYRQQNPC LVQHLGELIP1020
 1021 VFASVLTGSP EQLNDELRSE LLSMVKEIAP QYESVVSNYP QLVALLQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1067] PSI-BLAST 60.39794 Crystal Structure of The Cand1-Cul1-Roc1 Complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  4.58709163830613 bayes_pls_golite062009
  • binding
    		•  3.0667965351474 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  2.74547353635661 bayes_pls_golite062009
  • transporter activity
    		•  2.48700774379895 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.26725422172281 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  1.91487015967262 bayes_pls_golite062009
  • protein binding
    		•  1.73688475473996 bayes_pls_golite062009
  • nuclear export signal receptor activity
    		•  1.29390474721722 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.28481004323799 bayes_pls_golite062009
  • RNA binding
    		•  1.20550543134698 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.09652988954158 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.00841167631924 bayes_pls_golite062009
  • signal transducer activity
    		•  0.662662274021266 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.662662274021266 bayes_pls_golite062009
  • signal sequence binding
    		•  0.57106697498903 bayes_pls_golite062009
  • structural molecule activity
    		•  0.449804281824548 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.385452858197632 bayes_pls_golite062009
  • DNA binding
    		•  0.309260217284589 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252495966234234 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.248585912061178 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.226380819487924 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.217517113570989 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.178770060806735 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.175241020572885 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.174922130116569 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.100181463251306 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0635404099346928 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0548082069333885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.052195223119721 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0405268469927988 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle