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Protein Overview: git5

General Information:
Name(s) found: git5 / SPBC32H8.07 [Sanger Pombe]
Description(s) found:
Found 22 descriptions.
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  • heterotrimeric G protein beta subunit Git5 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 305 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    heterotrimeric G-protein complex [TASLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: activation of adenylate cyclase activity by glucose-triggered G-protein signaling pathway [TASLink to PubMed article]
    G-protein coupled receptor protein signaling pathway [TASLink to PubMed article]
    negative regulation of transcription by glucose [IMPLink to PubMed article]
    negative regulation of conjugation with cellular fusion [TASLink to PubMed article]
    activation of adenylate cyclase activity [TASLink to PubMed article]
    cAMP-mediated signaling [IMPLink to PubMed article]
    Molecular Function: signal transducer activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSGSRVNVN IQGTRVLKNK LGKIPDIDIS TDGKYLLSAS TNDVLLVWDL HTSNKVAFFE  60
   61 APSVWIMTCA FSPSTKSIAA GGLNNFCVVY DTSVPDADPV ELVGHAGFVS CCKYVDDGHL 120
  121 LTGSGDKTCM FWDIEQAKAI SVLKGHEMDI VSLDFLPSNP NLFVTGGCDK LAKLWDLRAA 180
  181 YCCATFPGNT SDINSISFFP SNADFVTGAE DGIARCFDIR ASAEIFQYSS PSSSPINSVL 240
  241 FSKSGKLLFI AKDKTCEVWD SISSKTITSL TGHENRISSL ALTSDGTMLA TGSWDECVRL 300
  301 WSSSG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..305] PSI-BLAST 65.221849 beta1-subunit of the signal-transducing G protein heterotrimer

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
    		• 6.67009948605948 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K4 specific)
    		•  4.71992275913384 bayes_pls_golite062009
  • GTPase activity
    		•  4.02994814377904 bayes_pls_golite062009
  • RNA binding
    		•  3.77273677738815 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.25521258308263 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.3610959773142 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.30918780727915 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.29049708962212 bayes_pls_golite062009
  • snoRNA binding
    		•  2.27164613239345 bayes_pls_golite062009
  • protein binding
    		•  2.26925404328312 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  2.10926890165617 bayes_pls_golite062009
  • dynactin binding
    		•  2.07556426531897 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.85632145559025 bayes_pls_golite062009
  • DNA binding
    		•  1.71685536470455 bayes_pls_golite062009
  • myosin heavy chain kinase activity
    		•  1.67241027239254 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.53722103498827 bayes_pls_golite062009
  • structural molecule activity
    		•  1.47097979074281 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.41752877005447 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  1.35170368882651 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.26395898062853 bayes_pls_golite062009
  • transporter activity
    		•  1.17433526848815 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • receptor activity
    		•  1.12819778129653 bayes_pls_golite062009
  • actin binding
    		•  1.08902852052152 bayes_pls_golite062009
  • transcription factor activity
    		•  1.08768505897883 bayes_pls_golite062009
  • mRNA binding
    		•  1.05053985350578 bayes_pls_golite062009
  • myosin II binding
    		•  0.990046481880222 bayes_pls_golite062009
  • actin filament binding
    		•  0.976656531652978 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • signal transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
  • type 1 angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
  • kinase activity
    		•  0.807669232329985 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.805273887494167 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.703671430935754 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • dynein binding
    		•  0.67053085134802 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.634547834947756 bayes_pls_golite062009
  • protein kinase activity
    		•  0.544118712921054 bayes_pls_golite062009
  • transcription factor binding
    		•  0.489473003915035 bayes_pls_golite062009
  • tubulin binding
    		•  0.418259033722167 bayes_pls_golite062009
  • microtubule binding
    		•  0.360612852884949 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30761651528651 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.161639372576406 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.0803897416817422 bayes_pls_golite062009
  • receptor binding
    		•  0.0390635451962911 bayes_pls_golite062009
  • kinase binding
    		•  0.0366162235750993 bayes_pls_golite062009
  • protein kinase binding
    		•  0.00858004043229577 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  0.00335766408304172 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle