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Any process involving glucose that stops, prevents or reduces the rate of transcription. The presence of glucose in the growth medium inhibits the synthesis of certain enzymes in bacteria growing on the medium. For example, transcription of some catabolic operons is under negative control by specific repressors and glucose is an anti-inducer of xylose utilization and glycerol kinase. Any process involving glucose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter. Any process involving carbon catabolites that modulates the frequency, rate or extent of transcription. Any process involving carbon catabolites that stops, prevents or reduces the rate of transcription. Carbon catabolite repression is a mechanism of genetic regulation in bacteria in which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances. Any process involving glucose that modulates the frequency, rate or extent or transcription. Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of transcription by glucose
Acc: GO:0045014
Aspect: Biological Process
Desc: Any process involving glucose that stops, prevents or reduces the rate of transcription. The presence of glucose in the growth medium inhibits the synthesis of certain enzymes in bacteria growing on the medium. For example, transcription of some catabolic operons is under negative control by specific repressors and glucose is an anti-inducer of xylose utilization and glycerol kinase.
Synonyms:
  • downregulation of transcription by glucose
  • inhibition of transcription by glucose
  • down-regulation of transcription by glucose
  • glucose effect
  • down regulation of transcription by glucose
  • glucose repression
Proteins in PDR annotated with:
   This term: 13 [Search]
   Term or descendants: 25 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045014 - negative regulation of transcription by glucose (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle