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Protein Overview: tuf1

General Information:
Name(s) found: tuf1 / SPBC9B6.04c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • mitochondrial translation elongation factor EF-Tu Tuf1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 439 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: mitochondrial translation [RCALink to PubMed article]
    translational elongation [IGILink to PubMed article]
    positive regulation of translational elongation [ICLink to PubMed article]
    mitochondrial genome maintenance [IMPLink to PubMed article]
    Molecular Function: GTP binding [ISSLink to PubMed article]
    translation elongation factor activity [ISSLink to PubMed article]
    GTPase activity [ISSLink to PubMed article]
    tRNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSAKATSLL FQGFRKNCLR LNRISFASGL INRFTVPART YADEKVFVRK KPHVNIGTIG  60
   61 HVDHGKTTLT AAITKCLSDL GQASFMDYSQ IDKAPEEKAR GITISSAHVE YETANRHYAH 120
  121 VDCPGHADYI KNMITGAATM DGAIIVVSAT DGQMPQTREH LLLARQVGVK QIVVYINKVD 180
  181 MVEPDMIELV EMEMRELLSE YGFDGDNTPI VSGSALCALE GREPEIGLNS ITKLMEAVDS 240
  241 YITLPERKTD VPFLMAIEDV FSISGRGTVV TGRVERGTLK KGAEIEIVGY GSHLKTTVTG 300
  301 IEMFKKQLDA AVAGDNCGLL LRSIKREQLK RGMIVAQPGT VAPHQKFKAS FYILTKEEGG 360
  361 RRTGFVDKYR PQLYSRTSDV TVELTHPDPN DSDKMVMPGD NVEMICTLIH PIVIEKGQRF 420
  421 TVREGGSTVG TALVTELLD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..439] PSI-BLAST 102.0 Elongation factor Tu (EF-Tu), domain 2; Elongation factor Tu (EF-Tu); Elongation factor Tu (EF-Tu), N-terminal (G) domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation elongation factor activity
    		•  8.90683166637832 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  4.8378725567094 bayes_pls_golite062009
  • translation regulator activity
    		•  4.79814772079421 bayes_pls_golite062009
  • binding
    		•  2.01755875920323 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.913322399315129 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.860102064846772 bayes_pls_golite062009
  • peptidyltransferase activity
    		•  0.705667095586631 bayes_pls_golite062009
  • motor activity
    		•  0.677658554107 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.569910969126728 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.568840867400671 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.568779924702229 bayes_pls_golite062009
  • nucleotide binding
    		•  0.564275755355315 bayes_pls_golite062009
  • DNA binding
    		•  0.376487324624615 bayes_pls_golite062009
  • ATP binding
    		•  0.1860481660648 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.152859582615242 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.150159515184919 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.147579541298736 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.138615225841109 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.133017653323467 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.11674780318211 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.113504049290503 bayes_pls_golite062009
  • structural molecule activity
    		•  0.11239762372728 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.111293884322157 bayes_pls_golite062009
  • protein binding
    		•  0.071010918255742 bayes_pls_golite062009
  • helicase activity
    		•  0.0450969969658499 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle