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Protein Overview: prp19

General Information:
Name(s) found: prp19 / SPAC29A4.08c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • ubiquitin-protein ligase E4 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 488 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    nucleus [IDALink to PubMed article]
    ubiquitin ligase complex [TASLink to PubMed article]
    cytoplasm [IDALink to PubMed article][ISSLink to PubMed article]
    spliceosomal complex [TASLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: RNA splicing, via transesterification reactions [ISSLink to PubMed article]
    nuclear mRNA splicing, via spliceosome [TASLink to PubMed article]
    protein ubiquitination [TASLink to PubMed article]
    ubiquitin-dependent protein catabolic process [ISSLink to PubMed article]
    Molecular Function: ubiquitin-protein ligase activity [TASLink to PubMed article]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFCSISGETP KEPVISRVSG NVYEKRLIEQ VIRETSKDPV TQQECTLEDL VPVKVPDFVR  60
   61 PRPPSATSLP ALLSLFQEEW DSVALEQFEL RRNLTETKQE LSTALYSLDA ALRVISRLTK 120
  121 ERDEAREALA KFSDNIGTVS SKTIEVQEVE MGESDDQLKT SLRSTVEKTF QELSSKRKRT 180
  181 KLQPKWATDD AVSQLLQATP STILENLETE STTSFFPSPE NSSFVLCLHK DELLCLDIQS 240
  241 NSTLKIFEGS ALACCWLTSS KIAVATADAI SIFEFPVSSS GLQSVGEPTS SIPIDEKVNF 300
  301 LQAHPSGEYL LAASNEKCYI FSLKSQVYNI TVAQHITSLA VHPDGNLFVA GLENGELRFF 360
  361 ETSSGNELTK FGPHSSPVKT LQFGENGYWL VVTTNDDSDI FIWDLRKSEL VQKIPLQTKV 420
  421 AAVSLDITSQ LLVSSDGETL YVHIYVKSSK SWRCMSQTHV SSISNLVWLN ELHQLLFSTS 480
  481 NGAILRLG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..93] FFAS03 4.68 Solution structure of the U-box in human ubiquitin conjugation factor E4A
    2 View Details [94..488] PSI-BLAST 55.30103 PAF-AH Holoenzyme: Lis1/Alfa2


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle