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Protein Overview: sec27

General Information:
Name(s) found: sec27 / SPBC16C6.13c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • coatomer beta' subunit [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 796 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    COPI vesicle coat [ISSLink to PubMed article]
    Biological Process: ER to Golgi vesicle-mediated transport [ISSLink to PubMed article]
    retrograde vesicle-mediated transport, Golgi to ER [ISSLink to PubMed article]
    intracellular protein transport [ICLink to PubMed article]
    late endosome to vacuole transport via multivesicular body sorting pathway [ISS]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRLDFQRKL LSHTERVKAV DFHPTEPWVI ASHYNGQVGI WNYNTQTLVR SFDINDVPIR  60
   61 ACAFIARKNW FVCGSDDFQV RVYNYNTGEK VTQFEAHPDY IRALVVHPTQ PFLLTSSDDM 120
  121 TIKCFNWDMS WKCVQTFEGH SRYVMSLAIN PKDTNTFASS CLDGTVKVWS FGSSVANFTL 180
  181 QAHDRGVNYV NYYPAGDKPY LITAGDDNLI KVWDYQTKAC VRILEGHTNN VSFAFFHSKF 240
  241 PIIISGSEDG TVKIWHTLSY SLIKSYNFSL DRAWCIAQNK DNGLVTVGFD NGLITFSLGR 300
  301 DEPSVTMDSS GKVVWSNYNE VMSAMIRPAK EQSDLTDGSL ISLSVKELGT TELYPAVLKH 360
  361 SPNGRFVSVC GNGEYIVYTA LAWRNKAYGK ALDFAWSADS NVYGSRTSDR SIVIHKNFKE 420
  421 SNRLDLSYSC DKIFGGFLLG VVGSDFICFY DWDTGILVRK IDVKPKGVYW NDDGRFVILA 480
  481 CDDDFYLLGF NAEMFYSAVE SGTADEEEGV ADSFEALADV SESVVNGKWV AETFIYTTTA 540
  541 ARLNYLIGDQ TYKIANVESS FYLLGYIPRD DRIYLTDRDM NVVSYSFNLA IIEYQSLVLK 600
  601 GDLEAAQGLL EQISETDRPR LSDFLSRLGY KEAALELSGD SVQRFELALD AQRLDIASQI 660
  661 AQELDDPLKW RSLGDAALNA WDFVLAQECF EKGKDYGSLV LLYTATNNHE GLKELSQLTK 720
  721 STKINNTAFI CSWLTNQPAE CVNILTSTQR YPEANLFAAT YCPDEVKNVL PEWKVDLTKN 780
  781 QKERIADSLG DLELKN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] PSI-BLAST 73.30103 No description for 2ovpB was found.
    2 View Details [109..637] PSI-BLAST 52.39794 Actin interacting protein 1
    3 View Details [638..796] FFAS03 1.6 No description for 2ifuA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • histone methyltransferase activity (H3-K4 specific)
    		•  4.71992275913384 bayes_pls_golite062009
  • GTPase activity
    		•  4.02994814377904 bayes_pls_golite062009
  • actin binding
    		•  3.31804728298431 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.25521258308263 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.1056443224755 bayes_pls_golite062009
  • tubulin binding
    		•  2.76945430061825 bayes_pls_golite062009
  • microtubule binding
    		•  2.72684103222924 bayes_pls_golite062009
  • dynein binding
    		•  2.54821997913979 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.3610959773142 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.30918780727915 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.29049708962212 bayes_pls_golite062009
  • dynactin binding
    		•  2.07556426531897 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.85632145559025 bayes_pls_golite062009
  • DNA binding
    		•  1.71685536470455 bayes_pls_golite062009
  • actin filament binding
    		•  1.5197243426595 bayes_pls_golite062009
  • structural molecule activity
    		•  1.47448876401574 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.41752877005447 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  1.35170368882651 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.22384651674093 bayes_pls_golite062009
  • protein binding
    		•  1.21879977456466 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  1.15313682561559 bayes_pls_golite062009
  • receptor activity
    		•  1.12819778129653 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  1.11754260203517 bayes_pls_golite062009
  • transcription factor activity
    		•  1.08768505897883 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  1.01166033978052 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • signal transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • protein transporter activity
    		•  0.964340340346761 bayes_pls_golite062009
  • type 1 angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
  • angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
    		• 0.88172763425403 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.734793983890004 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • transcription factor binding
    		•  0.489473003915035 bayes_pls_golite062009
  • dynein intermediate chain binding
    		•  0.443846546939402 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.426429095658617 bayes_pls_golite062009
  • kinase activity
    		•  0.387572734234845 bayes_pls_golite062009
  • snoRNA binding
    		•  0.347797037104681 bayes_pls_golite062009
  • receptor binding
    		•  0.316169754698691 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30761651528651 bayes_pls_golite062009
  • protein kinase activity
    		•  0.229242350006544 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.226335610368636 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.161639372576406 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.118975415284669 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  0.00335766408304172 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle