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Protein Overview: cdc10

General Information:
Name(s) found: cdc10 / SPBC336.12c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • MBF transcription factor complex subunit Cdc10 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 767 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    MBF transcription complex [TASLink to PubMed article]
    Biological Process: regulation of transcription, mitotic [IDALink to PubMed article]
    rRNA transcription [IDALink to PubMed article]
    positive regulation of transcription, mitotic [IDALink to PubMed article]
    negative regulation of transcription, mitotic [IDALink to PubMed article]
    regulation of transcription, meiotic [IDALink to PubMed article]
    negative regulation of transcription, meiotic [IDALink to PubMed article]
    regulation of transcription involved in G1/S-phase of mitotic cell cycle [TASLink to PubMed article]
    G1/S transition of mitotic cell cycle [TASLink to PubMed article]
    G1 phase of mitotic cell cycle [RCALink to PubMed article]
    mitotic anaphase [RCALink to PubMed article]
    regulation of S phase of mitotic cell cycle [IGILink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [RCALink to PubMed article]
    positive regulation of transcription, meiotic [IDALink to PubMed article]
    Molecular Function: transcription factor activity [ICLink to PubMed article]
    protein binding [IPILink to PubMed article]
    specific RNA polymerase II transcription factor activity [RCALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASANFIRQF ELGNDSFSYQ KRPEDEPSQP LSNRNINKLN DSSTLKDSSS RIFINSQVLR  60
   61 DGRPVELYAV ECSGMKYMEL SCGDNVALRR CPDSYFNISQ ILRLAGTSSS ENAKELDDII 120
  121 ESGDYENVDS KHPQIDGVWV PYDRAISIAK RYGVYEILQP LISFNLDLFP KFSKQQQIES 180
  181 SSISKNLNTS SFNTRSPLRN HNFSNPSKSS KNGVHTINNM QSSPSPSSSF LLPLTQIDSQ 240
  241 NVKRSNNYLS TSPPILEQRL KRHRIDVSDE DLHPSSQLND NEASSLFPDT PRLNHSLSFV 300
  301 SLVSSLPPLD QNIMQDYHTS KDILTSIFLD VNFADSSALE AKLSDSLDLD VPIDELGHAA 360
  361 LHWAAAVAKM PLLQALIHKG ANPLRGNLTG ETALMRSVLV TNHLNQNSFG DLLDLLYASL 420
  421 PCTDRAGRTV VHHICLTAGI KGRGSASRYY LETLLNWAKK HASGNNGYML KDFINYLNHQ 480
  481 DKNGDTALNI AARIGNKNIV EVLMQAGASA YIPNRAGLSV ANFGIFVENA LKQPEDSKQT 540
  541 KVSLMSENLS SKEKTAVPPR QKSRDIIASV TDVISSLDKD FQDEMAAKQS MIDSAYTQLR 600
  601 ESTKKLSDLR EQLHVSETQR TLFLELRQRC KNLMTSIEEQ KSELSNLYES FDPNGIHDSL 660
  661 SLDADAPFTV NENNNKNLSI AELKFQVAAY ERNEARLNEL ANKLWQRNSN IKSKCRRVVS 720
  721 LCTGVDESRV DSLLESLLQA VESDGQQGEV DMGRVAGFLR VVKEHQA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..131] PSI-BLAST 19.30103 DNA-binding domain of Mlu1-box binding protein MBP1
    2 View Details [132..511] PSI-BLAST 66.045757 Ankyrin-R
    3 View Details [512..767] PSI-BLAST 10.0 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • protein binding
    		•  2.69918165732603 bayes_pls_golite062009
  • binding
    		•  2.60916417202222 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.37103377984038 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.8957142857582 bayes_pls_golite062009
  • DNA binding
    		•  1.78305438715057 bayes_pls_golite062009
  • transcription activator activity
    		•  1.6418915400902 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.57265102061447 bayes_pls_golite062009
  • transcription factor activity
    		•  1.2667825651547 bayes_pls_golite062009
  • transcription factor binding
    		•  1.06366405671195 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.949906091645366 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  0.68541709976608 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.590503097160372 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  0.576422771673579 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.56201598804914 bayes_pls_golite062009
  • kinase regulator activity
    		•  0.4228431685549 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle