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Protein Overview: car1

General Information:
Name(s) found: car1 / SPBP26C9.02c [Sanger Pombe]
Description(s) found:
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  • pir||S45455 arginase (EC 3.5.3.1) - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|584770|sp|P37818.1|ARGI1_SCHPO RecName: Full=Arginase [NCBI NR]
  • gi|414914|emb|CAA53236.1| arginase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19111925|ref|NP_595133.1| arginase Car1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|10129774|emb|CAC08237.1| arginase Car1 [Schizosaccharomyces pombe] [NCBI NR]
  • arginase Car1 [Sanger Pombe]
  • Arginase OS=Schizosaccharomyces pombe GN=car1 PE=2 SV=1 [Swiss-Prot]
  • (P37818) Arginase (EC 3.5.3.1) [Swiss-Prot]
  • ARGINASE: P37818; [pompepVF.fasta]
  • Arginase (EC 3.5.3.1) [pompep4896]
  • |car1||arginase (PMID 7985419) [pompepnew.fasta]
  • |car1||arginase (PMID 7985419)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • |car1||arginase |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • arginase [Schizosaccharomyces pombe]gi|414914|emb|CAA53236.1| arginase [Schizosaccharomyces pombe]gi|10129774|emb|CAC08237.1| car1 [Schizosaccharomyces pombe]gi|584770|sp|P37818|ARG1_SCHPO Arginasegi|629893|pir||S45455 arginase (EC 3.5.3.1) - fission [nrdb_11152004_Chlamydomonas]
  • |car1||arginase Car1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • arginase [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Arginase [nr-271106-contam.fasta]
  • SPBP26C9.02c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • arginase [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Arginase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=car1 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 323 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article][IGILink to PubMed article]
    Biological Process: urea cycle [IEA]
    arginine catabolic process to ornithine [IGILink to PubMed article]
    Molecular Function: arginase activity [IGILink to PubMed article]
    manganese ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPHKIPEVH RHIMSSRYME GNAVSIINMP FSGGQPKDGA ELAPEMIEAA GLPEDLERLG  60
   61 YSVNVVQNPK FKSRPLKEGP NQALMKNPLY VSNVTRQVRN IVQQELEKQR IAVNIGGDHS 120
  121 LAIGTVEGVQ AVYDDACVLW IDAHADINTP DSSPSKNLHG CPLSFSLGYA EPLPEEFAWT 180
  181 RRVIEERRLA FIGLRDLDPM ERAFLRERSI TAYTMHDVDK YGIARVVEMA LEHINPGRRR 240
  241 PIHLSFDVDA CDPIVAPATG TRVPGGLTFR EAMYICESVA ETGSLVAVDV MEVNPLLGNK 300
  301 EEAKTTVDLA RSIVRTCLGQ TLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..323] PSI-BLAST 90.522879 Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arginase activity
    		•  6.53441421234691 bayes_pls_golite062009
  • agmatinase activity
    		•  3.73238467801147 bayes_pls_golite062009
  • protein deacetylase activity
    		•  3.15425266272734 bayes_pls_golite062009
  • histone deacetylase activity
    		•  3.10913119405575 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.52770743634098 bayes_pls_golite062009
  • hydrolase activity
    		•  2.11707868768295 bayes_pls_golite062009
  • transcription factor binding
    		•  2.06538836131829 bayes_pls_golite062009
  • binding
    		•  1.948738669065 bayes_pls_golite062009
  • deacetylase activity
    		•  1.91016771390707 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.72243397396987 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.70671280294121 bayes_pls_golite062009
  • catalytic activity
    		•  1.68836803454021 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.59562744871718 bayes_pls_golite062009
  • DNA binding
    		•  1.55288325159263 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
    		•  1.01223037319069 bayes_pls_golite062009
  • transcription factor activity
    		•  0.882841288306625 bayes_pls_golite062009
  • protein binding
    		•  0.725535842743004 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.68008378742866 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.52929003055123 bayes_pls_golite062009
  • enzyme binding
    		•  0.39566582482721 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.38389503761392 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  0.0917282383800223 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle