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View Structure Prediction Details

Protein: car1
Organism: Schizosaccharomyces pombe
Length: 323 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for car1.

Description E-value Query
Range
Subject
Range
ARGI2_RAT - Arginase-2, mitochondrial OS=Rattus norvegicus GN=Arg2 PE=2 SV=1
337.0 [0..9] [321..11]
ARGN2_XENLA - Arginase, non-hepatic 2 OS=Xenopus laevis GN=arg2-b PE=2 SV=1
336.0 [0..21] [321..25]
gi|118404488, gi... - gi|118404488|ref|NP_001072685.1| arginase 2 [Xenopus (Silurana) tropicalis], gi|116284136|gb|AAI2401...
335.0 [0..21] [321..25]
ARGI2_MOUSE - Arginase-2, mitochondrial OS=Mus musculus GN=Arg2 PE=1 SV=1
334.0 [0..9] [321..11]
gi|109084030 - gi|109084030|ref|XP_001107412.1| PREDICTED: arginase, type II isoform 1 [Macaca mulatta]
gi|90085519 - gi|90085519|dbj|BAE91500.1| unnamed protein product [Macaca fascicularis]
332.0 [0..22] [321..24]
ARGI2_SCHPO - Arginase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=aru1 PE=3 SV=1
SPAC3H1.07 - arginase
332.0 [0..1] [323..1]

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Predicted Domain #1
Region A:
Residues: [1-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPHKIPEVH RHIMSSRYME GNAVSIINMP FSGGQPKDGA ELAPEMIEAA GLPEDLERLG  60
   61 YSVNVVQNPK FKSRPLKEGP NQALMKNPLY VSNVTRQVRN IVQQELEKQR IAVNIGGDHS 120
  121 LAIGTVEGVQ AVYDDACVLW IDAHADINTP DSSPSKNLHG CPLSFSLGYA EPLPEEFAWT 180
  181 RRVIEERRLA FIGLRDLDPM ERAFLRERSI TAYTMHDVDK YGIARVVEMA LEHINPGRRR 240
  241 PIHLSFDVDA CDPIVAPATG TRVPGGLTFR EAMYICESVA ETGSLVAVDV MEVNPLLGNK 300
  301 EEAKTTVDLA RSIVRTCLGQ TLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.522879
Match: 1pq3A
Description: Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
arginase activity 6.53441421234691 bayes_pls_golite062009
agmatinase activity 3.73238467801147 bayes_pls_golite062009
protein deacetylase activity 3.15425266272734 bayes_pls_golite062009
histone deacetylase activity 3.10913119405575 bayes_pls_golite062009
transcription regulator activity 2.52770743634098 bayes_pls_golite062009
hydrolase activity 2.11707868768295 bayes_pls_golite062009
transcription factor binding 2.06538836131829 bayes_pls_golite062009
binding 1.948738669065 bayes_pls_golite062009
deacetylase activity 1.91016771390707 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.72243397396987 bayes_pls_golite062009
transcription repressor activity 1.70671280294121 bayes_pls_golite062009
catalytic activity 1.68836803454021 bayes_pls_golite062009
nucleic acid binding 1.59562744871718 bayes_pls_golite062009
DNA binding 1.55288325159263 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1.01223037319069 bayes_pls_golite062009
transcription factor activity 0.882841288306625 bayes_pls_golite062009
protein binding 0.725535842743004 bayes_pls_golite062009
transcription cofactor activity 0.68008378742866 bayes_pls_golite062009
transcription corepressor activity 0.52929003055123 bayes_pls_golite062009
enzyme binding 0.39566582482721 bayes_pls_golite062009
specific transcriptional repressor activity 0.38389503761392 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 0.0917282383800223 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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