Protein Overview: FBpp0292968, Tao...

General Information:
Name(s) found:	FBpp0292968 [FlyBase] Tao-1-PD / FBpp0074541 [FlyBase] Tao-1-PE / FBpp0074540 [FlyBase]
Description(s) found: Found 40 descriptions. SHOW ALL	type=protein; loc=X:complement(19465614..19465737,19465808..19465926,19465999..19466220,19466285..19466458,19466530..19466646,19466711..19466833,19466899..19467261,19467324..19467497,19469391..19470002,19470072..19470428,19470728..19471232,19471298..19471527); ID=FBpp0292968; name=Tao-PF; parent=FBgn0031030,FBtr0303999; dbxref=FlyBase:FBpp0292968,FlyBase_Annotation_IDs:CG14217-PF,REFSEQ:NP_001188672,GB_protein:ADV37754; MD5=e6c4d8101d54c2b0372bfcaf2e6ae04c; length=1039; release=r5.56; species=Dmel; [FlyBase] The gene Tao-1 is referred to in FlyBase by the symbol Dmel\Tao-1 (CG14217, FBgn0031030). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19465181..19473842. It has the cytological map location 18D2-18D3. There is experimental evidence that it has the molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: apoptosis. 5 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene Tao-1 is referred to in FlyBase by the symbol Dmel\Tao-1 (CG14217, FBgn0031030). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19465181..19473842. It has the cytological map location 18D2-18D3. There is experimental evidence that it has the molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: apoptosis. 5 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1039 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	apoptosis [IMP] protein amino acid phosphorylation [IEA][NAS]
Molecular Function:	ATP binding [IEA] receptor signaling protein serine/threonine kinase activity [NAS] protein serine/threonine kinase activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSARPGSLK DPEIADLFNK HDPEKIFEDL REIGHGSFGA VYYARCNLTR EIVAIKKMSY  60
   61 TGKQSQEKWQ DILKEIRFLR QLNHPNTIEY KGCYLRESTA WLVMEYCVGS ASDIIEVHKK 120
  121 PLHEDEIAAI CLGVLSGLSY LHSLGRIHRD IKAGNILLTD NGVVKLADFG SAAIKCPANS 180
  181 FVGTPYWMAP EVILAMDEGQ YDGKVDVWSL GITCIELAER KPPYFNMNAM SALYHIAQNE 240
  241 SPTLPKNDWS DAFCSFVELC LKKMPAERPS SAKLLTHAYV TRPRSDTVLL ELIARTKSAV 300
  301 RELDNLNYRK MKKILMVDTC ETESAVGDTD DQQDDHAGGD SSKSNSITSE HSIHSVGVSA 360
  361 ASSQSSSSNS IPAAAQNHHH IAAHHHQQAA SAAVAAAMHH HHHPHQQPPP SWPSGQQGQP 420
  421 VPPGAVSRNS SRHRNRPPLP NIMHSMNNNV TPTNSASVVP APAPAPVLPP PISVLPHLSA 480
  481 MGHVGGGGTG TGGSGGGSPA SGGPLADRIQ PVQPRYLTTP AAQAAVYAAS SASSQQAISN 540
  541 AVNDHGPNNF ATIRTTSIVT KQQKEHMQEE MHEQMSGYKR MRREHQAHLV KLEEKCKVDM 600
  601 EAHKTALDKE YDTLLHNFTR DLDRLETKHQ QDVERRAKQT SAAEKKLHKE ITLKQENDRK 660
  661 VYDLNRKKEY KANKERWKRE LSMDESTPKR QRDLTLQSQK DNLKQHEAQE EQRMLQAQKQ 720
  721 YIELEMRKFK RKRMIMQHEH EDQQLRDELG KKEQQLQQAH AMLLKHHEKT QELEYRQQKS 780
  781 VHQLREEQIN KQHDTELHNQ KDYMDRIKKE LVRKHAVELR QQPKSLKQKE LQIRKQFRET 840
  841 CKTQTKQYKR YKAQVLQTTP KEQQKEVIKQ LKEEKHRKLT LLGEQYEQSI ADMFQSQSYK 900
  901 LDESQVIECQ RTHEQLEYEL EMLTAYQNKN KKQAQEQRDR ERRELENRVS VRRGLLENKM 960
  961 DAELQQFNQE RAERLRMKHE KHTKELEAFD NESIALGFST LSLIEVSREA YADEEGSLSG1020
 1021 SMISLAHSNS STSFPAGSL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
phosphotransferase activity, alcohol group as acceptor	5.49988294224815	bayes_pls_golite062009
protein kinase activity	5.4586557943719	bayes_pls_golite062009
kinase activity	5.3287080791198	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	4.96052051118534	bayes_pls_golite062009
protein serine/threonine kinase activity	4.46381887831481	bayes_pls_golite062009
transferase activity	3.97138602499442	bayes_pls_golite062009
binding	2.74863538127007	bayes_pls_golite062009
protein binding	2.276111749106	bayes_pls_golite062009
ATP binding	1.97600611746091	bayes_pls_golite062009
adenyl ribonucleotide binding	1.93596671856664	bayes_pls_golite062009
adenyl nucleotide binding	1.90928021591891	bayes_pls_golite062009
purine ribonucleotide binding	1.65732943334212	bayes_pls_golite062009
ribonucleotide binding	1.65726906484847	bayes_pls_golite062009
purine nucleotide binding	1.63763394711025	bayes_pls_golite062009
nucleotide binding	1.63195828048121	bayes_pls_golite062009
MAP kinase kinase activity	1.42275431028856	bayes_pls_golite062009
protein tyrosine kinase activity	1.3898059094397	bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity	1.38496328649031	bayes_pls_golite062009
receptor signaling protein activity	1.27291233344322	bayes_pls_golite062009
catalytic activity	1.21655087018101	bayes_pls_golite062009
cytoskeletal protein binding	1.1208666000428	bayes_pls_golite062009
actin binding	1.00749371062134	bayes_pls_golite062009
cyclin-dependent protein kinase activity	0.959360414036299	bayes_pls_golite062009
MAP kinase activity	0.81943579965027	bayes_pls_golite062009
nucleic acid binding	0.655396214040669	bayes_pls_golite062009
transcription regulator activity	0.631882811427766	bayes_pls_golite062009
DNA binding	0.599969415455862	bayes_pls_golite062009
protein serine/threonine/tyrosine kinase activity	0.48345772948903	bayes_pls_golite062009
enzyme binding	0.46284745266176	bayes_pls_golite062009
transcription factor activity	0.457173041568166	bayes_pls_golite062009
kinase binding	0.443916188551908	bayes_pls_golite062009
magnesium ion binding	0.393328812780268	bayes_pls_golite062009
MAP kinase kinase kinase activity	0.37115026509016	bayes_pls_golite062009
protein kinase binding	0.285611963740145	bayes_pls_golite062009
signal transducer activity	0.270054246024761	bayes_pls_golite062009
molecular transducer activity	0.270054246024761	bayes_pls_golite062009
transmembrane receptor protein kinase activity	0.0556163711947139	bayes_pls_golite062009
transmembrane receptor activity	0.00652065412910241	bayes_pls_golite062009

Term	Confidence	Notes
binding	2.58108937165812	bayes_pls_golite062009
protein binding	2.33863707177656	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..316]	PSI-BLAST	70.69897	Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K
2	View Details	[317..719]	FFAS03	1.34	crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution
3	View Details	[720..1039]	PSI-BLAST	16.69897	Heavy meromyosin subfragment

Protein Overview: FBpp0292968, Tao...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: